LY-255582

LY-255582 Structure
LY-255582 structure
Common Name LY-255582
CAS Number 119193-09-8 Molecular Weight 345.51900
Density N/A Boiling Point N/A
Molecular Formula C22H35NO2 Melting Point N/A
MSDS USA Flash Point N/A

Activation of mesolimbic dopamine neurons during novel and daily limited access to palatable food is blocked by the opioid antagonist LY255582.

Am. J. Physiol. Regul. Integr. Comp. Physiol. 295(2) , R463-71, (2008)

An analog of the trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine series (LY255582) exhibits high in vitro binding affinity and antagonist potency for the mu-, delta-, and kappa-opioid receptors. In vivo, LY255582 exhibits potent effects in reducing food inta...