GSK-1016790A
GSK-1016790A structure
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Common Name | GSK-1016790A | ||
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| CAS Number | 942206-85-1 | Molecular Weight | 655.61300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H32Cl2N4O6S2 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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Angiotensin II induces membrane trafficking of natively expressed transient receptor potential vanilloid type 4 channels in hypothalamic 4B cells.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 307(8) , R945-55, (2014) Transient receptor potential vanilloid family type 4 (TRPV4) channels are expressed in central neuroendocrine neurons and have been shown to be polymodal in other systems. We previously reported that in the rodent, a model of dilutional hyponatremia associate... |
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Opposing actions of TRPV4 channel activation in the lung vasculature.
Respir. Physiol. Neurobiol. 219 , 43-50, (2015) Transient receptor potential vanilloid 4 (TRPV4) calcium channels are known to promote endothelium-dependent relaxation of mouse mesenteric arteries but TRPV4's role in the pulmonary vasculature is uncertain. Thus, we characterized TRPV4 channel vascular tone... |
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A mutation in TRPV4 results in altered chondrocyte calcium signaling in severe metatropic dysplasia.
Am. J. Med. Genet. A 167A , 2286-93, (2015) Transient receptor potential cation channel, subfamily V, member 4 (TRPV4) is a polymodal modulated non-selective cation channel required for normal development and maintenance of bone and cartilage. Heterozygous mutations of this channel cause a variety of c... |