![]() H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-OH structure
|
Common Name | H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-OH | ||
---|---|---|---|---|
CAS Number | 20845-02-7 | Molecular Weight | 1759.01 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C85H123N21O20 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | N/A |
Biomolecular imaging with a C60-SIMS/MALDI dual ion source hybrid mass spectrometer: instrumentation, matrix enhancement, and single cell analysis.
J. Am. Soc. Mass Spectrom. 25(11) , 1897-907, (2014) We describe a hybrid MALDI/C(60)-SIMS Q-TOF mass spectrometer and corresponding sample preparation protocols to image intact biomolecules and their fragments in mammalian spinal cord, individual invertebrate neurons, and cultured neuronal networks. A lateral ... |
|
V-type nerve agents phosphonylate ubiquitin at biologically relevant lysine residues and induce intramolecular cyclization by an isopeptide bond.
Anal. Bioanal. Chem 406(21) , 5171-85, (2014) Toxic organophosphorus compounds (e.g., pesticides and nerve agents) are known to react with nucleophilic side chains of different amino acids (phosphylation), thus forming adducts with endogenous proteins. Most often binding to serine, tyrosine, or threonine... |
|
Mass Spectrometry Imaging and GC-MS Profiling of the Mammalian Peripheral Sensory-Motor Circuit.
J. Am. Soc. Mass Spectrom. 26 , 958-66, (2015) Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) has evolved to become an effective discovery tool in science and clinical diagnostics. Here, chemical imaging approaches are applied to well-defined regions of the mammalian p... |
|
Benzimidazole, coumrindione and flavone derivatives as alternate UV laser desorption ionization (LDI) matrices for peptides analysis.
Chem. Cent. J. 7 , 77, (2013) Matrix-assisted laser desorption/ionization (MALDI) is a soft ionization mass spectrometric technique, allowing the analysis of bio-molecules and other macromolecules. The matrix molecules require certain characteristic features to serve in the laser desorpti... |
|
Prostaglandin E-prostanoid4 receptor mediates angiotensin II-induced (pro)renin receptor expression in the rat renal medulla.
Hypertension 64(2) , 369-77, (2014) Angiotensin II (Ang II) stimulates (pro)renin receptor (PRR) expression in the renal collecting duct, triggering the local renin response in the distal nephron. Our recent study provided evidence for involvement of cyclooxygenase-2-prostaglandin E2 pathway in... |
|
Identification of bona fide alternative renin transcripts expressed along cortical tubules and potential roles in promoting insulin resistance in vivo without significant plasma renin activity elevation.
Hypertension 64(1) , 125-33, (2014) Renin belongs to a family of aspartyl proteases and is the rate-limiting enzyme in the synthesis of the potent vasoactive peptide angiotensin II. Processing of renal renin has been extensively investigated in juxtaglomerular granular cells, in which prorenin ... |
|
COX-2 mediates angiotensin II-induced (pro)renin receptor expression in the rat renal medulla.
Am. J. Physiol. Renal Physiol. 307(1) , F25-32, (2014) (Pro)renin receptor (PRR) is predominantly expressed in the distal nephron where it is activated by angiotensin II (ANG II), resulting in increased renin activity in the renal medulla thereby amplifying the de novo generation and action of local ANG II. The g... |
|
Therapeutic vaccines against human and rat renin in spontaneously hypertensive rats.
PLoS ONE 8 , e66420, (2013) Vaccination provides a promising approach for treatment of hypertension and improvement in compliance. As the initiation factor of renin-angiotensin system, renin plays a critical role in hypertension. In this study, we selected six peptides (rR32, rR72, rR21... |
|
Angiotensin II increases the expression of (pro)renin receptor during low-salt conditions.
Am. J. Med. Sci. 348(5) , 416-22, (2014) Evidence indicates that chronic angiotensin II (AngII) infusion increases (pro)renin receptor ((P)RR) expression in renal inner medullary collecting duct (IMCD) cells. Recently, it has been shown that renal (P)RR expression is augmented during a low-salt (LS)... |
|
Quantitative measurements of cell-cell signaling peptides with single-cell MALDI MS.
Anal. Chem. 80 , 7128-7136, (2008) Cell-to-cell signaling peptides play important roles in neurotransmission, neuromodulation, and hormonal signaling. Significant progress has been achieved in qualitative investigations of signaling peptides in the nervous system using single cell matrix-assis... |