L-(+)-Lactic acid sodium salt
L-(+)-Lactic acid sodium salt structure
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Common Name | L-(+)-Lactic acid sodium salt | ||
|---|---|---|---|---|
| CAS Number | 867-56-1 | Molecular Weight | 112.060 | |
| Density | 1.33 | Boiling Point | 227.6ºC at 760 mmHg | |
| Molecular Formula | C3H5NaO3 | Melting Point | 163-165ºC | |
| MSDS | Chinese USA | Flash Point | 109.9ºC | |
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Real-Time Monitoring of Cellular Bioenergetics with a Multianalyte Screen-Printed Electrode.
Anal. Chem. 87 , 7857-64, (2015) Real-time monitoring of changes to cellular bioenergetics can provide new insights into mechanisms of action for disease and toxicity. This work describes the development of a multianalyte screen-printed electrode for the detection of analytes central to cell... |
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Warburg-like Glycolysis and Lactate Shuttle in Mouse Decidua during Early Pregnancy.
J. Biol. Chem. 290 , 21280-91, (2015) Decidualization is an essential process of maternal endometrial stromal cells to support pregnancy. Although it is known that enhanced glucose influx is critical for decidualization, the underlying mechanism in regulating glucose metabolism in decidua remains... |
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Carbonic anhydrase inhibitors. Inhibition of the beta-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with aliphatic and aromatic carboxylates.
Bioorg. Med. Chem. 17 , 2654-7, (2009) The inhibition of the beta-carbonic anhydrases (CAs, EC 4.2.1.1) from the pathogenic fungi Cryptococcus neoformans (Can2) and Candida albicans (Nce103) with carboxylates such as the C1-C5 aliphatic carboxylates, oxalate, malonate, maleate, malate, pyruvate, l... |
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Evaluation of an electrochemical biosensor for uric acid measurement in human whole blood samples.
Clin. Chim. Acta 436 , 72-7, (2014) Uric acid measurement has become increasingly important, and electrochemically modified detection method based portable devices hold a dominant position in the market for point of care and self-monitoring of uric acid blood levels. However, there has been a l... |
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PDADMAC flocculation of Chinese hamster ovary cells: enabling a centrifuge-less harvest process for monoclonal antibodies.
MAbs 7(2) , 413-28, (2015) High titer (>10 g/L) monoclonal antibody (mAb) cell culture processes are typically achieved by maintaining high viable cell densities over longer culture durations. A corresponding increase in the solids and sub-micron cellular debris particle levels are als... |
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Suppression of microbial metabolic pathways inhibits the generation of the human body odor component diacetyl by Staphylococcus spp.
PLoS ONE 9(11) , e111833, (2014) Diacetyl (2,3-butanedione) is a key contributor to unpleasant odors emanating from the axillae, feet, and head regions. To investigate the mechanism of diacetyl generation on human skin, resident skin bacteria were tested for the ability to produce diacetyl v... |
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Evidences of basal lactate production in the main white adipose tissue sites of rats. Effects of sex and a cafeteria diet.
PLoS ONE 10(3) , e0119572, (2015) Female and male adult Wistar rats were fed standard chow or a simplified cafeteria diet for one month. Then, the rats were killed and the white adipose tissue (WAT) in four sites: perigonadal, retroperitoneal, mesenteric and subcutaneous (inguinal) were sampl... |
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Robust Generation of Cardiomyocytes from Human iPS Cells Requires Precise Modulation of BMP and WNT Signaling.
Stem Cell Rev. 11 , 560-9, (2015) Various strategies have been published enabling cardiomyocyte differentiation of human induced pluripotent stem (iPS) cells. However the complex nature of signaling pathways involved as well as line-to-line variability compromises the application of a particu... |
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The small molecule GMX1778 is a potent inhibitor of NAD+ biosynthesis: strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-deficient tumors.
Mol. Cell. Biol. 29(21) , 5872-88, (2009) GMX1777 is a prodrug of the small molecule GMX1778, currently in phase I clinical trials for the treatment of cancer. We describe findings indicating that GMX1778 is a potent and specific inhibitor of the NAD(+) biosynthesis enzyme nicotinamide phosphoribosyl... |
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Lactate promotes resistance to glucose starvation via upregulation of Bcl-2 mediated by mTOR activation.
Oncol. Rep. 33(2) , 875-84, (2014) Solid tumors grow faster and need more glucose than normal tissue; however, due to poor angiogenesis and excessive growth, tumors remote from blood vessels are always under glucose starvation. Even so, cancer cells remain alive in vivo. Thus, making cancer ce... |