2-(6-METHOXY-3-OXO-2,3-DIHYDRO-1H-INDEN-1-YL)ACETIC ACID

2-(6-METHOXY-3-OXO-2,3-DIHYDRO-1H-INDEN-1-YL)ACETIC ACID Structure
2-(6-METHOXY-3-OXO-2,3-DIHYDRO-1H-INDEN-1-YL)ACETIC ACID structure
Common Name 2-(6-METHOXY-3-OXO-2,3-DIHYDRO-1H-INDEN-1-YL)ACETIC ACID
CAS Number 24467-92-3 Molecular Weight 220.22100
Density 1.286g/cm3 Boiling Point 428.7ºC at 760mmHg
Molecular Formula C12H12O4 Melting Point 139-144ºC(lit.)
MSDS Chinese USA Flash Point 170.6ºC

Selective inhibition of the chymotrypsin-like activity of the 20S proteasome by 5-methoxy-1-indanone dipeptide benzamides.

Bioorg. Med. Chem. Lett. 8(3) , 209-14, (1998)

Potent inhibitors of the 20S proteasome that contain a novel indanone head group coupled to di and tripeptides are described. These compounds are the first proteasome inhibitors have demonstrated high selectivity for the chymotrypsin-like activity of the 20S ...