Boc-Cys(Trt)-OH

Boc-Cys(Trt)-OH Structure
Boc-Cys(Trt)-OH structure
Common Name Boc-Cys(Trt)-OH
CAS Number 21947-98-8 Molecular Weight 463.589
Density 1.2±0.1 g/cm3 Boiling Point 610.9±55.0 °C at 760 mmHg
Molecular Formula C27H29NO4S Melting Point 143-146 °C(lit.)
MSDS USA Flash Point 323.3±31.5 °C

Synthesis and biological evaluation of L-cysteine derivatives as mitotic kinesin Eg5 inhibitors.

Bioorg. Med. Chem. Lett. 17 , 3921-4, (2007)

Inhibition of Eg5 represents a novel approach for the treatment of cancer. Here, we report the synthesis and structure-activity relationship of S-trityl-L-cysteine (STLC) derivatives as Eg5 inhibitors. Some of these derivatives such as 4f demonstrated enhance...