Calcineurin Substrate trifluoroacetate salt
Calcineurin Substrate trifluoroacetate salt structure
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Common Name | Calcineurin Substrate trifluoroacetate salt | ||
|---|---|---|---|---|
| CAS Number | 113873-67-9 | Molecular Weight | 2112.35000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C92H150N28O29 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Endoplasmic reticulum vacuolation and unfolded protein response leading to paraptosis like cell death in cyclosporine A treated cancer cervix cells is mediated by cyclophilin B inhibition.
Biochim. Biophys. Acta 1843(11) , 2497-512, (2014) Cyclosporine A (CsA), a widely used immunosuppressant shows cytotoxic effects by either inducing apoptosis or redirecting the cell towards non-apoptotic cell death. However, there still remains a lacuna in understanding the mechanism of CsA induced non-apopto... |
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Myocyte enhancer factor (MEF)-2 plays essential roles in T-cell transformation associated with HTLV-1 infection by stabilizing complex between Tax and CREB.
Retrovirology 12 , 23, (2015) The exact molecular mechanisms regarding HTLV-1 Tax-mediated viral gene expression and CD4 T-cell transformation have yet to be fully delineated. Herein, utilizing virus-infected primary CD4+ T cells and the virus-producing cell line, MT-2, we describe the in... |
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Nonradioactive assay for protein phosphatase 2B (calcineurin) activity using a partial sequence of the subunit of cAMP-dependent protein kinase as substrate.
Anal. Biochem. 216 , 147, (1994) Currently, protein phosphatase 2B (calcineurin) activity is assayed based on release of [32P]phosphate from a 19-amino acid peptide (partial sequence of the regulatory subunit of cAMP-dependent protein kinase) following its [32P]ATP phosphorylation using the ... |