N-Phthaloylglycine

N-Phthaloylglycine Structure
N-Phthaloylglycine structure
Common Name N-Phthaloylglycine
CAS Number 4702-13-0 Molecular Weight 205.167
Density 1.5±0.1 g/cm3 Boiling Point 412.6±28.0 °C at 760 mmHg
Molecular Formula C10H7NO4 Melting Point 193-196 °C(lit.)
MSDS Chinese USA Flash Point 203.3±24.0 °C

N-phthaloyl-glycine-hydroxamic acid as serum iron chelator in rats.

Acta. Pharm. 58(2) , 231-6, (2008)

The aim of this study was to investigate the activity of N-phthaloyl-glycine-hydroxamic acid (Phth-Gly-HA) as a new iron chelator in vivo to be used in iron overload diseases. After intraperitoneal application of Phth-Gly-HA to male rats (1 mg kg(-1) body mas...

Comparative pharmacokinetic and pharmacodynamic analysis of phthaloyl glycine derivatives with potential antiepileptic activity.

Pharm. Res. 11(10) , 1429-34, (1994)

Glycine, in addition to GABA, is one of the most important neurotransmitter amino acids. The described structure pharmacokinetic pharmacodynamic relationships (SPPR) study explored the possibility of utilizing phthaloyl derivatives of glycine as new antiepile...

Synthesis, crystal structure, DNA binding and in vitro biological studies of Ni(II), Cu(II) and Zn(II) complexes of N-phthaloylglycine.

J. Photochem. Photobiol. B, Biol. 117 , 228-39, (2012)

Ni(II), Cu(II) and Zn(II) metal complexes of N-phthaloylglycine were synthesized, characterized, reported for single crystal X-ray diffraction analysis for Ni(II) complex, and investigated for their binding with DNA under physiological conditions, using spect...