Escitalopram oxalate
Escitalopram oxalate structure
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Common Name | Escitalopram oxalate | ||
|---|---|---|---|---|
| CAS Number | 219861-08-2 | Molecular Weight | 414.427 | |
| Density | N/A | Boiling Point | 428.3ºC at 760 mmHg | |
| Molecular Formula | C22H23FN2O5 | Melting Point | 152-153ºC | |
| MSDS | Chinese USA | Flash Point | 212.8ºC | |
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The effect of combined treatment with risperidone and antidepressants on the MK-801-induced deficits in the social interaction test in rats.
Pharmacol. Rep. 67 , 1183-7, (2015) Several clinical reports have suggested that augmentation of atypical antipsychotics' activity by antidepressants may efficiently improve the treatment of negative and some cognitive symptoms of schizophrenia.The aim of the present study was to investigate th... |
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Prolonged administration of antidepressant drugs leads to increased binding of [(3)H]MPEP to mGlu5 receptors.
Neuropharmacology 84 , 46-51, (2014) Metabotropic glutamate 5 (mGlu5) receptors are functionally connected with NMDA receptors. The antidepressant activity of the NMDA receptor antagonist ketamine in both preclinical and clinical studies, along with the antidepressant-like activities of negative... |
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Prenatal stress, regardless of concurrent escitalopram treatment, alters behavior and amygdala gene expression of adolescent female rats.
Neuropharmacology 97 , 251-8, (2015) Depression during pregnancy has been linked to in utero stress and is associated with long-lasting symptoms in offspring, including anxiety, helplessness, attentional deficits, and social withdrawal. Depression is diagnosed in 10-20% of expectant mothers, but... |
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Acute serotonergic treatment changes the relation between anxiety and HPA-axis functioning and periaqueductal gray activation.
Behav. Brain Res. 273 , 155-65, (2014) Serotonergic (5-HT) drugs are widely used in the clinical management of mood and anxiety disorders. However, it is reported that acute 5-HT treatment elicits anxiogenic-like behavior. Interestingly, the periaqueductal gray (PAG), a midbrain structure which re... |
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Effects of serotonergic medications on locomotor performance in humans with incomplete spinal cord injury.
J. Neurotrauma 31(15) , 1334-42, (2014) Incomplete spinal cord injury (iSCI) often results in significant motor impairments that lead to decreased functional mobility. Loss of descending serotonergic (5HT) input to spinal circuits is thought to contribute to motor impairments, with enhanced motor f... |
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The Escitalopram versus Electric Current Therapy for Treating Depression Clinical Study (ELECT-TDCS): rationale and study design of a non-inferiority, triple-arm, placebo-controlled clinical trial.
Sao. Paulo Med. J. 133 , 252-63, (2015) Major depressive disorder (MDD) is a common psychiatric condition, mostly treated with antidepressant drugs, which are limited due to refractoriness and adverse effects. We describe the study rationale and design of ELECT-TDCS (Escitalopram versus Electric Cu... |