5-Benzyloxyindole

5-Benzyloxyindole Structure
5-Benzyloxyindole structure
Common Name 5-Benzyloxyindole
CAS Number 1215-59-4 Molecular Weight 223.270
Density 1.2±0.1 g/cm3 Boiling Point 411.6±20.0 °C at 760 mmHg
Molecular Formula C15H13NO Melting Point 100-104 °C(lit.)
MSDS Chinese USA Flash Point 148.9±12.0 °C

5-benzyloxytryptamine as an antagonist of TRPM8.

Bioorg. Med. Chem. Lett. 20 , 7076-9, (2010)

5-Benzyloxytryptamine 19 was found to act as an antagonist of the TRPM8 ion-channel. For example, 19 had an IC(50) of 0.34 μM when menthol was used as the stimulating agonist. Related commercially-available tryptamine derivatives showed diminished, or no anta...