5-Chloroindole
5-Chloroindole structure
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Common Name | 5-Chloroindole | ||
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| CAS Number | 17422-32-1 | Molecular Weight | 151.593 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 293.0±13.0 °C at 760 mmHg | |
| Molecular Formula | C8H6ClN | Melting Point | 69-71 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 158.9±5.4 °C | |
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Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography.
J. Med. Chem. 52 , 4694-715, (2009) We describe a novel fragment library termed fragments of life (FOL) for structure-based drug discovery. The FOL library includes natural small molecules of life, derivatives thereof, and biaryl protein architecture mimetics. The choice of fragments facilitate... |
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5-Chloroindole: a potent allosteric modulator of the 5-HT₃ receptor.
Br. J. Pharmacol. 169(6) , 1228-38, (2013) The 5-HT₃ receptor is a ligand-gated ion channel that is modulated allosterically by various compounds including colchicine, alcohols and volatile anaesthetics. However the positive allosteric modulators (PAMs) identified to date have low affinity, which hind... |
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Multicomponent phenol hydroxylase-catalysed formation of hydroxyindoles and dyestuffs from indole and its derivatives.
Lett. Appl. Microbiol. 41(2) , 163-8, (2005) To establish multicomponent phenol hydroxylases (mPHs) as novel biocatalysts for producing dyestuffs and hydroxyindoles such as 7-hydroxyindole (7-HI) from indole and its derivatives.We have isolated Pseudomonas sp. KL33, which possesses a phenol degradation ... |
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Indole and 5-chloroindole as inhibitors of anodic dissolution and cathodic deposition of copper in acidic chloride solutions. Scendo M, et al.
J. Appl. Electrochem. 33(3-4) , 287-293., (2003)
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5-Amino-and 5-chloro-indole as mild steel corrosion inhibitors in 1 N sulphuric acid. Moretti G, et al.
Electrochim. Acta 41(13) , 1971-80, (1996)
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Fluorescence properties of electropolymerised 5-substituted indoles in solution. Jennings P, et al.
J. Chem. Soc., Faraday 94(24) , 3619-24, (1998)
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Synthesis of Some 5-and 6-Chloro, 5-Methyl, and 5, 6, 7-Trimethyl Derivatives of Tryptamine. Benington F, et al.
J. Org. Chem. 25(9) , 1542-47, (1960)
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Indigo and indirubin derivatives from indoles in Polygonum tinctorium tissue cultures. Shim JY, et al.
Biotechnol. Lett. 20(12) , 1139-1143, (1998)
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Fluorescence properties of electropolymerised 5-substituted indoles in solution. Jennings P, et al.
J. Chem. Soc., Faraday Trans. 94(24) , 3619-3624, (1998)
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