Tricaprilin
Tricaprilin structure
|
Common Name | Tricaprilin | ||
|---|---|---|---|---|
| CAS Number | 538-23-8 | Molecular Weight | 470.682 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 508.0±17.0 °C at 760 mmHg | |
| Molecular Formula | C27H50O6 | Melting Point | 9-10 °C | |
| MSDS | Chinese USA | Flash Point | 209.3±21.0 °C | |
|
Stimulation of mild, sustained ketonemia by medium-chain triacylglycerols in healthy humans: estimated potential contribution to brain energy metabolism.
Nutrition 29(4) , 635-40, (2013) In humans consuming a normal diet, we investigated 1) the capacity of a medium-chain triacylglycerol (MCT) supplement to stimulate and sustain ketonemia, 2) ¹³C-β-hydroxybutyrate and ¹³C-trioctanoate metabolism, and 3) the theoretical contribution of the degr... |
|
|
Immobilised lipase for in vitro lipolysis experiments.
J. Pharm. Sci. 104(4) , 1311-8, (2015) In vitro lipolysis experiments are used to assess digestion of lipid-based formulations, and probe solubilisation by colloidal phases during digestion. However, proteins and other biological components in the pancreatin often used as the lipase result in high... |
|
|
Chain length affects pancreatic lipase activity and the extent and pH-time profile of triglyceride lipolysis.
Eur. J. Pharm. Biopharm. 93 , 353-62, (2015) Triglycerides (TG) are one of the most common excipients used in oral lipid-based formulations. The chain length of the TG plays an important role in the oral bioavailability of the co-administered drug. Fatty acid (FA) chain-length specificity of porcine pan... |
|
|
Comparative uterotrophic effects of endoxifen and tamoxifen in ovariectomized Sprague-Dawley rats.
Toxicol. Pathol. 42(8) , 1188-96, (2014) Endoxifen (4-hydroxy-N-desmethyl-tamoxifen), one of the major active metabolites of tamoxifen, has substantially greater estrogen antagonist properties and antiproliferative effects in breast tumor cells than tamoxifen, a mixed estrogen agonist/antagonist. An... |
|
|
Surface properties of artificial tear film lipid layers: effects of wax esters.
Invest. Ophthalmol. Vis. Sci. 55(7) , 4448-54, (2014) The tear film lipid layer is believed to stabilize the tear film and to retard evaporation. Based on previous simple in vitro studies, the evidence for the latter property is scarce. In this study, we used complex lipid mixtures including various wax esters t... |
|
|
5-demethylnobiletin promotes the formation of polymerized tubulin, leads to G2/M phase arrest and induces autophagy via JNK activation in human lung cancer cells.
J. Nutr. Biochem. 26 , 484-504, (2015) 5-Demethylnobiletin is a hydroxylated polymethoxyflavone found in citrus plants that shows antiproliferative activities in several cancer cell lines. In this study, we investigated the effects and underlying molecular mechanisms of 5-demethylnobiletin on inhi... |
|
|
Biochemical characterization of Yarrowia lipolytica LIP8, a secreted lipase with a cleavable C-terminal region.
Biochim. Biophys. Acta 1851(2) , 129-40, (2015) Yarrowia lipolytica is a lipolytic yeast possessing 16 paralog genes coding for lipases. Little information on these lipases has been obtained and only the major secreted lipase, namely YLLIP2, had been biochemically and structurally characterized. Another se... |
|
|
Supported inhibitor for fishing lipases in complex biological media and mass spectrometry identification.
Biochimie 107 Pt A , 124-34, (2014) A synthetic phosphonate inhibitor designed for lipase inhibition but displaying a broader range of activity was covalently immobilized on a solid support to generate a function-directed tool targeting serine hydrolases. To achieve this goal, straightforward a... |
|
|
Porcine pancreatic lipase related protein 2 has high triglyceride lipase activity in the absence of colipase.
Biochim. Biophys. Acta 1831(9) , 1435-41, (2013) Efficient dietary fat digestion is essential for newborns who consume more dietary fat per body weight than at any other time of life. In many mammalian newborns, pancreatic lipase related protein 2 (PLRP2) is the predominant duodenal lipase. Pigs may be an e... |
|
|
High-throughput screening method for lipases/esterases.
Methods Mol. Biol. 861 , 89-100, (2012) High-throughput screening (HTS) methods for lipases and esterases are generally performed by using synthetic chromogenic substrates (e.g., p-nitrophenyl, resorufin, and umbelliferyl esters) which may be misleading since they are not their natural substrates (... |