Cefuroxime
Cefuroxime structure
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Common Name | Cefuroxime | ||
|---|---|---|---|---|
| CAS Number | 55268-75-2 | Molecular Weight | 424.385 | |
| Density | 1.8±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C16H16N4O8S | Melting Point | 171.5-173°C | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Antibiotic exposure in a low-income country: screening urine samples for presence of antibiotics and antibiotic resistance in coagulase negative staphylococcal contaminants.
PLoS ONE 9(12) , e113055, (2014) Development of antimicrobial resistance has been assigned to excess and misuse of antimicrobial agents. Staphylococci are part of the normal flora but are also potential pathogens that have become essentially resistant to many known antibiotics. Resistances i... |
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Beta- lactam antibiotics stimulate biofilm formation in non-typeable haemophilus influenzae by up-regulating carbohydrate metabolism.
PLoS ONE 9(7) , e99204, (2014) Non-typeable Haemophilus influenzae (NTHi) is a common acute otitis media pathogen, with an incidence that is increased by previous antibiotic treatment. NTHi is also an emerging causative agent of other chronic infections in humans, some linked to morbidity,... |
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Pharmacokinetics of cefuroxime in porcine cortical and cancellous bone determined by microdialysis.
Antimicrob. Agents Chemother. 58(6) , 3200-5, (2014) Traditionally, the pharmacokinetics of antimicrobials in bone have been investigated using bone biopsy specimens, but this approach suffers from considerable methodological limitations. Consequently, new methods are needed. The objectives of this study were t... |
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Cross-platform toxicogenomics for the prediction of non-genotoxic hepatocarcinogenesis in rat.
PLoS ONE 9(5) , e97640, (2014) In the area of omics profiling in toxicology, i.e. toxicogenomics, characteristic molecular profiles have previously been incorporated into prediction models for early assessment of a carcinogenic potential and mechanism-based classification of compounds. Tra... |
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Assessment of indications for percutaneous endoscopic gastrostomy--development of a predictive model.
Scand. J. Gastroenterol. 50(2) , 245-52, (2015) Percutaneous endoscopic gastrostomy (PEG) is used for long-term enteral nutrition in neurological patients with dysphagia (NEUR), in head and neck cancer patients prior to chemoradiation therapy (head and neck malignancy group [HNM]), or in cases of oropharyn... |
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Nonoperative management of perforated diverticulitis with extraluminal air is safe and effective in selected patients.
Dis. Colon Rectum 57(7) , 875-81, (2014) The optimal treatment for diverticulitis with extraluminal air is controversial.The purpose of this research was to evaluate the safety and effectiveness of nonoperative treatment of acute diverticulitis with extraluminal air.This was a retrospective cohort.T... |
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Genetic and structural insights into the dissemination potential of the extremely broad-spectrum class A beta-lactamase KPC-2 identified in an Escherichia coli strain and an Enterobacter cloacae strain isolated from the same patient in France.
Antimicrob. Agents Chemother. 52 , 3725-36, (2008) Two clinical strains of Escherichia coli (2138) and Enterobacter cloacae (7506) isolated from the same patient in France and showing resistance to extended-spectrum cephalosporins and low susceptibility to imipenem were investigated. Both strains harbored the... |
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Prevalence and Susceptibility Pattern of Multi Drug Resistant Clinical Isolates of Pseudomonas aeruginosa in Karachi.
Pak. J. Med. Sci. 30(5) , 951-4, (2014) To determine the frequency and susceptibility pattern of multi-drug resistant (MDR) Pseudomonas aeruginosa isolated from clinical specimens in Karachi.This cross sectional study was conducted in Microbiology Department, University of Karachi, from January 201... |
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Structural and biochemical characterization of VIM-26 shows that Leu224 has implications for the substrate specificity of VIM metallo-β-lactamases.
FEBS J. 282(6) , 1031-42, (2015) During the last decades antimicrobial resistance has become a global health problem. Metallo-β-lactamases (MBLs) which are broad-spectrum β-lactamases that inactivate virtually all β-lactams including carbapenems, are contributing to this health problem. In t... |
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A multicopy sRNA of Listeria monocytogenes regulates expression of the virulence adhesin LapB.
Nucleic Acids Res. 42(14) , 9383-98, (2014) The multicopy sRNA LhrC of the intracellular pathogen Listeria monocytogenes has been shown to be induced under infection-relevant conditions, but its physiological role and mechanism of action is not understood. In an attempt to pinpoint the exact terms of L... |