CP-20961
CP-20961 structure
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Common Name | CP-20961 | ||
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| CAS Number | 35607-20-6 | Molecular Weight | 667.18700 | |
| Density | 0.892g/cm3 | Boiling Point | 717.6ºC at 760mmHg | |
| Molecular Formula | C43H90N2O2 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 294.3ºC | |
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Identification of arthritogenic adjuvants of self and foreign origin.
Scand. J. Immunol. 49(1) , 45-50, (1999) The lack of defined triggers for human inflammatory joint diseases warrants efforts to identify candidate molecules. For this task, it may be an important lead that nonspecific activation of the immune system can precipitate arthritis in rats. Consequently, a... |
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A 71-kD heat shock protein (hsp) from Mycobacterium tuberculosis has modulatory effects on experimental rat arthritis.
Clin. Exp. Immunol. 103(1) , 77-82, (1996) The effects of a mycobacterial 71-kD hsp antigen have been investigated for its ability to modulate arthritis in rats. Subcutaneous injection (base of tail) of increasing amounts of hsp71 from Mycobacterium tuberculosis (MTB) produced dose-dependent different... |
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Effect of the bacillus of Calmette-Guérin, Propionibacter acnes and avridine as immunomodulators in antirabies vaccination of mice using the Fuenzalida-Palacios mouse brain vaccine.
Vaccine 17(19) , 2446-52, (1999) Using the laboratory mice, Fuenzalida-Palacios mouse brain human rabies vaccine was administered in groups of animals previously inoculated with rabies virus and then submitted to treatments with the immunomodulators onco-BCG, avridine and Propionibacterium a... |
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Arthritis in Lewis rats induced by the non-immunogenic adjuvant CP20961: an immunohistochemical analysis of the developing disease.
Ann. Rheum. Dis. 53(10) , 653-8, (1994) The role of lymphocytes and macrophages in developing adjuvant arthritis induced by an injection of CP20961 in inbred Lewis rats was studied over a 32 day period using a novel biotin-avidin immunoperoxidase histochemical technique.Fresh frozen sections of hin... |
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Improvement of the immune response to foot and mouth disease virus vaccine in calves by using Avridine as adjuvant.
Vet. Immunol. Immunopathol. 69(1) , 11-22, (1999) The epidemiological analysis of the cattle population during the eradication plan of foot and mouth disease (FMD) in Argentina clearly indicated a higher incidence of the disease in animals within their first year of age. It is important to improve the effica... |
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Avridine and LPS from Brucella ovis: effect on the memory induced by foot-and-mouth disease virus vaccination in mice.
Vaccine 11(13) , 1295-301, (1993) Foot-and-mouth disease is one of the more economically important diseases among meat-producing biungulate species. In contrast to natural infection, current foot-and-mouth disease virus (FMDV) vaccines, prepared with inactivated virus and adjuvants, elicit sh... |
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Is tolerance induction a possible mode of action of OM-89?
Drugs Exp. Clin. Res. 21(6) , 207-10, (1995) Neonatal Wistar rats were injected intraperitoneally with either 20 mu g OM-89 at birth and on day 3 after birth or 2 mg three times weekly until 200 g body weight. At this weight, groups were either implanted subcutaneously with a cotton pellet to induce gra... |
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Modulation of the antigen presentation activity in foot and mouth disease virus (FMDV) vaccines by two adjuvants: avridine and a water soluble fraction of Mycobacterium sp.
Vaccine 16(17) , 1627-32, (1998) We have previously demonstrated that the presence of the antigen presenting cells (APC) is critical in the induction and maintenance of the immune response in animals infected or immunized with inactivated FMDV. The use of immunological adjuvants has been rep... |
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Effect of Mycobacterium sp. wall and Avridine on the antibody response, IgG isotype profile and proliferative response induced by foot and mouth disease virus (FMDV) vaccination in cattle.
Vaccine 17(4) , 345-52, (1999) Different immunomodulators have been previously tested in our laboratory as enhancers of the specific immune response to FMDV vaccines in a murine model [2-4]. Here, we present results of two of these immunomodulators, a water-soluble fraction of the cell wal... |
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Administration of intraliposomal CP20961 to mice activates peritoneal macrophages and augments serum antibody response to Toxoplasma gondii.
J. Eukaryot. Microbiol. 41(5) , 12S, (1994)
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