ys-035 hcl
ys-035 hcl structure
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Common Name | ys-035 hcl | ||
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| CAS Number | 33978-72-2 | Molecular Weight | 359.45900 | |
| Density | 1.07g/cm3 | Boiling Point | 475.2ºC at 760 mmHg | |
| Molecular Formula | C21H29NO4 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 131.7ºC | |
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Carbamazepine and L-type calcium channel inhibitors: a binding assay study.
Biol. Psychiatry 39(11) , 979-81, (1996)
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Effect of alteration of nerve terminal Ca2+ regulation on increased spontaneous quantal release of acetylcholine by methyl mercury.
Toxicol. Appl. Pharmacol. 94(1) , 55-65, (1988) Agents known to disrupt intraterminal Ca2+ buffering, N,N-dimethylamino-8-octyl-3,4,5-trimethoxybenzoate (TMB-8), 25 microM; caffeine, 7.5 mM; N,N-bis(3,4-dimethoxyphenethyl)-N-methylamine (YS035), 180 microM; ouabain, 200 microM; and dantrolene, 50 microM, w... |
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Electrophysiological characterization of class III activity of a verapamil derivative in guinea-pig cardiac tissues.
Arzneimittelforschung 43(3) , 302-8, (1993) In isolated guinea-pig papillary muscle ([K+]o: 4.7 mmol/l, stimulation rate: 1 Hz) the verapamil derivative NN-bis-(3,4-dimethoxyphenethyl)-N-methylamine)-HCl (YS035; 0.3-100 mumol/l) increased the action potential duration measured at 90% repolarization lev... |
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Hyperpolarization-activated current, Ih, in inspiratory brainstem neurons and its inhibition by hypoxia.
Eur. J. Neurosci. 12(2) , 520-6, (2000) A hyperpolarization-activated current, Ih, is often implied in pacemaker-like depolarizations during rhythmic oscillatory activity. We describe Ih in the isolated respiratory centre of immature mice (P6-P11). Ih was recorded in 15% (22/146) of all inspiratory... |
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Properties of a new calcium ion antagonist on cellular uptake and mitochondrial efflux of calcium ions.
Biochem. J. 218(3) , 899-905, (1984) Compound YS 035 [NN-bis-(3,4-dimethoxyphenethyl)-N-methylamine] is a new synthetic compound capable of inhibiting Ca2+ uptake by different cells. The inhibition of Ca2+ uptake by muscle cells isolated from chicken embryo is dose-dependent in the compound YS 0... |
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Inhibition of potassium outward currents and pacemaker current in sheep cardiac Purkinje fibres by the verapamil derivative YS 035.
Naunyn Schmiedebergs Arch. Pharmacol. 344(6) , 653-61, (1991) The electrophysiologic mode of action and potency of the verapamil derivative YS 035 (N,N-bis-(3,4-dimethoxyphenethyl)-N-methyl amine) were investigated in sheep cardiac Purkinje fibres. Action potential duration measured at a repolarization level of -60 mV (... |