NH 125

NH 125 Structure
NH 125 structure
Common Name NH 125
CAS Number 278603-08-0 Molecular Weight 524.564
Density N/A Boiling Point N/A
Molecular Formula C27H45IN2 Melting Point 88.2-94.9ºC
MSDS Chinese USA Flash Point N/A

Inhibition of AMP-activated protein kinase signaling alleviates impairments in hippocampal synaptic plasticity induced by amyloid β.

J. Neurosci. 34(36) , 12230-8, (2014)

The AMP-activated protein kinase (AMPK) is a Ser/Thr kinase that is activated in response to low-energy states to coordinate multiple signaling pathways to maintain cellular energy homeostasis. Dysregulation of AMPK signaling has been observed in Alzheimer's ...