(1S,5R)-(-)-2-OXABICYCLO[3.3.0]OCT-6-EN-3-ONE

(1S,5R)-(-)-2-OXABICYCLO[3.3.0]OCT-6-EN-3-ONE Structure
(1S,5R)-(-)-2-OXABICYCLO[3.3.0]OCT-6-EN-3-ONE structure
Common Name (1S,5R)-(-)-2-OXABICYCLO[3.3.0]OCT-6-EN-3-ONE
CAS Number 43119-28-4 Molecular Weight 124.137
Density 1.2±0.1 g/cm3 Boiling Point 263.1±39.0 °C at 760 mmHg
Molecular Formula C7H8O2 Melting Point 44-46ºC(lit.)
MSDS Chinese USA Flash Point 104.0±24.5 °C

Characterization of the PON1 active site using modeling simulation, in relation to PON1 lactonase activity

Bioorg. Med. Chem. 16 , 7504-9, (2008)

Paraoxonase1 (PON1) is a HDL bound enzyme and many of the anti-atherogenic properties of HDL are attributed to PON1. The enzyme precise mechanism of protective action and its endogenous substrate remain elusive. PON1 hydrolyzes organophosphates, arylesters an...