BZ-ALA-OH
BZ-ALA-OH structure
|
Common Name | BZ-ALA-OH | ||
|---|---|---|---|---|
| CAS Number | 2198-64-3 | Molecular Weight | 193.199 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 452.3±28.0 °C at 760 mmHg | |
| Molecular Formula | C10H11NO3 | Melting Point | 163-164ºC | |
| MSDS | Chinese USA | Flash Point | 227.4±24.0 °C | |
|
pH-dependent hydrolase, glutaminase, transpeptidase and autotranspeptidase activities of Bacillus subtilis γ-glutamyltransferase.
FEBS J. 281(1) , 232-45, (2014) γ-Glutamyltransferases (γ-GTs) are heterodimeric enzymes that catalyze the transfer of a γ-glutamyl group from a donor species to an acceptor molecule in a transpeptidation reaction through the formation of an intermediate γ-glutamyl enzyme. In our search for... |
|
|
A mathematical model of tryptophan metabolism via the kynurenine pathway provides insights into the effects of vitamin B-6 deficiency, tryptophan loading, and induction of tryptophan 2,3-dioxygenase on tryptophan metabolites.
J. Nutr. 143(9) , 1509-19, (2013) Vitamin B-6 deficiency is associated with impaired tryptophan metabolism because of the coenzyme role of pyridoxal 5'-phosphate (PLP) for kynureninase and kynurenine aminotransferase. To investigate the underlying mechanism, we developed a mathematical model ... |
|
|
Bacterial CS2 hydrolases from Acidithiobacillus thiooxidans strains are homologous to the archaeal catenane CS2 hydrolase.
J. Bacteriol. 195(18) , 4046-56, (2013) Carbon disulfide (CS(2)) and carbonyl sulfide (COS) are important in the global sulfur cycle, and CS(2) is used as a solvent in the viscose industry. These compounds can be converted by sulfur-oxidizing bacteria, such as Acidithiobacillus thiooxidans species,... |
|
|
Mechanistic studies of protein arginine deiminase 2: evidence for a substrate-assisted mechanism.
Biochemistry 53(27) , 4426-33, (2014) Citrullination, which is catalyzed by protein arginine deiminases (PADs 1-4 and 6), is a post-translational modification (PTM) that effectively neutralizes the positive charge of a guanidinium group by its replacement with a neutral urea. Given the sequence s... |
|
|
The human peptidylarginine deiminases type 2 and type 4 have distinct substrate specificities
Biochim. Biophys. Acta 1844(4) , 829-36, (2014) Human peptidylarginine deiminases (hPADs) have been implicated in several diseases, particularly in rheumatoid arthritis. Since hPAD2 and hPAD4 are the isotypes expressed in the inflamed joints of RA patients and protein citrullination by PADs has been propos... |
|
|
A substrate-assisted mechanism of nucleophile activation in a Ser-His-Asp containing C-C bond hydrolase.
Biochemistry 52(42) , 7428-38, (2013) The meta-cleavage product (MCP) hydrolases utilize a Ser-His-Asp triad to hydrolyze a carbon-carbon bond. Hydrolysis of the MCP substrate has been proposed to proceed via an enol-to-keto tautomerization followed by a nucleophilic mechanism of catalysis. Keton... |
|
|
SUMOylation and deimination of proteins: two epigenetic modifications involved in Giardia encystation.
Biochim. Biophys. Acta 1843(9) , 1805-17, (2014) SUMOylation, a posttranslational modification of proteins, has been recently described as vital in eukaryotic cells. In a previous work, we analyzed the role of SUMO protein and the genes encoding the putative enzymes of the SUMOylation pathway in the parasit... |
|
|
Formiminoglutamase from Trypanosoma cruzi is an arginase-like manganese metalloenzyme.
Biochemistry 52(51) , 9294-309, (2013) The crystal structure of formiminoglutamase from Trypanosoma cruzi (TcFIGase) is reported at 1.85 Å resolution. Although the structure of this enzyme was previously determined by the Structural Genomics of Pathogenic Protozoa Consortium (PDB accession code 2A... |
|
|
LinA2, a HCH-converting bacterial enzyme that dehydrohalogenates HBCDs.
Chemosphere 107 , 194-202, (2014) Hexabromocyclododecanes (HBCDs) and hexachlorocyclohexanes (HCHs) are lipophilic, polyhalogenated hydrocarbons with comparable stereochemistry. Bacterial evolution in HCH-contaminated soils resulted in the development of several Spingomonadaceae which express... |
|
|
Crystal structure and site-directed mutagenesis analyses of haloalkane dehalogenase LinB from Sphingobium sp. strain MI1205.
J. Bacteriol. 195(11) , 2642-51, (2013) The enzymes LinB(UT) and LinB(MI) (LinB from Sphingobium japonicum UT26 and Sphingobium sp. MI1205, respectively) catalyze the hydrolytic dechlorination of β-hexachlorocyclohexane (β-HCH) and yield different products, 2,3,4,5,6-pentachlorocyclohexanol (PCHL) ... |