12-hydroxydodecanoic acid
12-hydroxydodecanoic acid structure
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Common Name | 12-hydroxydodecanoic acid | ||
|---|---|---|---|---|
| CAS Number | 505-95-3 | Molecular Weight | 216.31700 | |
| Density | 0.988g/cm3 | Boiling Point | 359.2ºC at 760 mmHg | |
| Molecular Formula | C12H24O3 | Melting Point | 85-88ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 185.2ºC | |
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Simultaneous radiometric and fluorimetric detection of lauric acid metabolites using high-performance liquid chromatography following esterification with 4-bromomethyl-6,7-dimethoxycoumarin in human and rat liver microsomes.
J. Chromatogr. B, Biomed. Appl. 681(2) , 233-9, (1996) The formation of (omega-1)-hydroxylauric acid from lauric acid (LA) can be used as an indicator of the activity of cytochrome P450 2E1 (CYP2E1) in rat and human liver microsomes. A high-performance liquid chromatographic (HPLC) method that is capable of ident... |
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Characterization of sophorolipid biosynthetic enzymes from Starmerella bombicola.
FEMS Yeast Res. 15 , (2015) Altering glycolipid structure by genetic engineering of Starmerella bombicola is a recently started research topic and worthy alternative to the unsuccessful selective feeding strategies conventionally applied to reach this goal. One question to be addressed ... |
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Formation of 20-oxoleukotriene B4 by an alcohol dehydrogenase isolated from human neutrophils.
Biochim. Biophys. Acta 1043(1) , 52-6, (1990) When 20-hydroxyleukotriene B4 (20-OH-LTB4) is incubated at pH 10.5 in the presence of NAD+ with an alcohol dehydrogenase isolated from human neutrophils, a polar product is formed as detected on reverse-phase high-performance liquid chromatography (RP-HPLC). ... |
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Lipase-catalyzed synthesis and properties of poly[(12-hydroxydodecanoate)-co-(12-hydroxystearate)] directed towards novel green and sustainable elastomers.
Macromol. Biosci. 8(1) , 38-45, (2008) Novel green and sustainable elastomers having both good biodegradability and chemical recyclability properties were designed and synthesized using potentially biobased materials and lipase as an environmentally benign catalyst. High molecular weight poly[(12-... |
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The omega-hydroxlyation of lauric acid: oxidation of 12-hydroxlauric acid to dodecanedioic acid by a purified recombinant fusion protein containing P450 4A1 and NADPH-P450 reductase.
Arch. Biochem. Biophys. 330(1) , 199-208, (1996) The recombinant fusion protein rF450[mRat4Al/mRatOR]L1, containing the heme domain of P450 4A1 and the flavin domains of NADPH-P450 reductase, when incubated with dilaurylphosphatidylcholine (DLPC), Chaps, cytochrome b5, and a 20-fold excess of purified NADPH... |
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Crystal structures of mouse class II alcohol dehydrogenase reveal determinants of substrate specificity and catalytic efficiency.
J. Mol. Biol. 302(2) , 441-53, (2000) The structure of mouse class II alcohol dehydrogenase (ADH2) has been determined in a binary complex with the coenzyme NADH and in a ternary complex with both NADH and the inhibitor N-cyclohexylformamide to 2.2 A and 2.1 A resolution, respectively. The ADH2 d... |
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Production of new-to-nature sophorolipids by cultivating the yeast Candida bombicola on unconventional hydrophobic substrates.
Biotechnol. Bioeng. 108(4) , 734-41, (2011) The naturally occurring sophorolipids synthesized by Candida bombicola possess--despite their overall heterogeneity--little variation in the length of the lipid tail. The range is limited to C16-C18 fatty acids and is governed by the specificity of a cytochro... |
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Kinetic mechanism of human glutathione-dependent formaldehyde dehydrogenase.
Biochemistry 39(35) , 10720-9, (2000) Formaldehyde, a major industrial chemical, is classified as a carcinogen because of its high reactivity with DNA. It is inactivated by oxidative metabolism to formate in humans by glutathione-dependent formaldehyde dehydrogenase. This NAD(+)-dependent enzyme ... |
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Polymerized phosphatidyl choline vesicles. Stabilized and controllable time-release carriers.
Biochem. Biophys. Res. Commun. 101(1) , 131-6, (1981)
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CYP2M1: cloning, sequencing, and expression of a new cytochrome P450 from rainbow trout liver with fatty acid (omega-6)-hydroxylation activity.
Arch. Biochem. Biophys. 352(2) , 271-80, (1998) A cDNA clone was isolated from a female rainbow trout liver lambda g tau 11 library using polyclonal antibodies raised against rainbow trout cytochrome P450 LMC1. This 2149-nucleotide clone contained an open reading frame encoding a protein of 499 amino acids... |