Fibrin
Fibrin structure
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Common Name | Fibrin | ||
|---|---|---|---|---|
| CAS Number | 9001-31-4 | Molecular Weight | 145.16000 | |
| Density | 1.146g/cm3 | Boiling Point | 471.7ºC at 760mmHg | |
| Molecular Formula | C5H11N3O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 239.1ºC | |
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Thrombin inhibition with dabigatran protects against high-fat diet-induced fatty liver disease in mice.
J. Pharmacol. Exp. Ther. 351(2) , 288-97, (2014) Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of obesity and metabolic syndrome. Robust coagulation cascade activation is common in obese patients with NAFLD. We identified a critical temporal relationship between thrombin generation a... |
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Novel thrombolytic protease from edible and medicinal plant Aster yomena (Kitam.) Honda with anticoagulant activity: purification and partial characterization.
J. Biosci. Bioeng. 118(4) , 372-7, (2014) A thrombolytic protease named kitamase possessing anticoagulant property was purified from edible and medicinal plant Aster yomena (Kitam.) Honda. Kitamase showed a molecular weight of 50 kDa by SDS-PAGE and displayed a strong fibrin zymogram lysis band corre... |
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The effect of etanercept on lung leukocyte margination and fibrin deposition after cardiac surgery.
Am. J. Respir. Crit. Care Med. 188(6) , 751-4, (2013)
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Fibrin accumulation secondary to loss of plasmin-mediated fibrinolysis drives inflammatory osteoporosis in mice.
Arthritis Rheumatology 66(8) , 2222-33, (2014) Osteoporosis is a skeletal disorder characterized by low bone mass and increased bone fragility associated with aging, menopause, smoking, obesity, or diabetes. Persistent inflammation has been identified as an instigating factor in progressive bone loss. In ... |
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Platelet-rich preparations to improve healing. Part I: workable options for every size practice.
J. Oral Implantol. 40(4) , 500-10, (2014) Numerous studies have demonstrated that platelet-rich preparations applied to surgical sites, injuries, or wounds are a safe and effective way to promote soft tissue healing and bone growth. Various protocols have been developed for preparing platelet-rich pr... |
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Effect of platelet-rich fibrin on frequency of alveolar osteitis following mandibular third molar surgery: a double-blinded randomized clinical trial.
J. Oral Maxillofac. Surg. 72(8) , 1463-7, (2014) To evaluate the effectiveness of platelet-rich fibrin (PRF) in preventing the development of alveolar osteitis (AO).In a double-blinded study, patients with bilateral impacted mandibular third molars underwent surgical extractions, with one socket receiving P... |
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Endocrine regulation of airway contractility is overlooked.
J. Endocrinol. 222(2) , R61-73, (2014) Asthma is a prevalent respiratory disorder triggered by a variety of inhaled environmental factors, such as allergens, viruses, and pollutants. Asthma is characterized by an elevated activation of the smooth muscle surrounding the airways, as well as a propen... |
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Glycosaminoglycan entrapment by fibrin in engineered heart valve tissues.
Acta Biomater. 9(9) , 8149-57, (2013) Tissue engineered heart valves (TEHVs) may provide a permanent solution to congenital heart valve disease by permitting somatic valve growth in the pediatric patient. However, to date, TEHV studies have focused primarily on collagen, the dominant component of... |
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Bleeding rate during oral surgery of oral anticoagulant therapy patients with associated systemic pathologic entities: a prospective study of more than 500 extractions.
J. Oral Maxillofac. Surg. 72(5) , 858-67, (2014) Oral anticoagulant therapy (OAT) patients have international normalized ratio (INR) safety windows for oral surgery, the lower limit of which is determined by the thromboembolic risk, with the upper limit typically 3.0. We sought to assess whether these limit... |
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Procoagulant platelets form an α-granule protein-covered "cap" on their surface that promotes their attachment to aggregates.
J. Biol. Chem. 288(41) , 29621-32, (2013) Strongly activated "coated" platelets are characterized by increased phosphatidylserine (PS) surface expression, α-granule protein retention, and lack of active integrin αIIbβ3. To study how they are incorporated into thrombi despite a lack of free activated ... |