![]() 2-Nitrodiphenyl sulfone structure
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Common Name | 2-Nitrodiphenyl sulfone | ||
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CAS Number | 31515-43-2 | Molecular Weight | 263.269 | |
Density | 1.4±0.1 g/cm3 | Boiling Point | 462.3±28.0 °C at 760 mmHg | |
Molecular Formula | C12H9NO4S | Melting Point | 145-148 °C(lit.) | |
MSDS | Chinese USA | Flash Point | 233.4±24.0 °C |
Diarylsulfones, a new chemical class of nonnucleoside antiviral inhibitors of human immunodeficiency virus type 1 reverse transcriptase.
Antimicrob. Agents Chemother. 37(4) , 754-60, (1993) A series of variously substituted diarylsulfones and related derivatives were found to prevent human immunodeficiency virus type 1 (HIV-1) replication and HIV-1-induced cell killing in vitro. One of the more potent derivatives, 2-nitrophenyl phenyl sulfone (N... |
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Synthesis of pyrryl aryl sulfones targeted at the HIV-1 reverse transcriptase.
Arch. Pharm. (Weinheim) 328(3) , 223-9, (1995) Various aryl 1-pyrryl sulfones were synthesized and tested as inhibitors of HIV-1. 2-Nitrophenyl-2-ethoxycarbonyl-1-pyrryl sulfone, the most active among test derivatives, was selected as lead compound of the aryl pyrryl sulfone series. The in vitro anti-HIV-... |
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