2-Nitrodiphenyl sulfone

2-Nitrodiphenyl sulfone Structure
2-Nitrodiphenyl sulfone structure
Common Name 2-Nitrodiphenyl sulfone
CAS Number 31515-43-2 Molecular Weight 263.269
Density 1.4±0.1 g/cm3 Boiling Point 462.3±28.0 °C at 760 mmHg
Molecular Formula C12H9NO4S Melting Point 145-148 °C(lit.)
MSDS Chinese USA Flash Point 233.4±24.0 °C

Diarylsulfones, a new chemical class of nonnucleoside antiviral inhibitors of human immunodeficiency virus type 1 reverse transcriptase.

Antimicrob. Agents Chemother. 37(4) , 754-60, (1993)

A series of variously substituted diarylsulfones and related derivatives were found to prevent human immunodeficiency virus type 1 (HIV-1) replication and HIV-1-induced cell killing in vitro. One of the more potent derivatives, 2-nitrophenyl phenyl sulfone (N...

Synthesis of pyrryl aryl sulfones targeted at the HIV-1 reverse transcriptase.

Arch. Pharm. (Weinheim) 328(3) , 223-9, (1995)

Various aryl 1-pyrryl sulfones were synthesized and tested as inhibitors of HIV-1. 2-Nitrophenyl-2-ethoxycarbonyl-1-pyrryl sulfone, the most active among test derivatives, was selected as lead compound of the aryl pyrryl sulfone series. The in vitro anti-HIV-...