D-Glucosamine hydrochloride
D-Glucosamine hydrochloride structure
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Common Name | D-Glucosamine hydrochloride | ||
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| CAS Number | 66-84-2 | Molecular Weight | 215.632 | |
| Density | N/A | Boiling Point | 449.9ºC at 760 mmHg | |
| Molecular Formula | C6H14ClNO5 | Melting Point | 190-194ºC | |
| MSDS | Chinese USA | Flash Point | 225.9ºC | |
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The hexosamine biosynthesis pathway and O-GlcNAcylation maintain insulin-stimulated PI3K-PKB phosphorylation and tumour cell growth after short-term glucose deprivation.
FEBS J. 281(16) , 3591-608, (2014) Glucose provides an essential nutrient source that supports glycolysis and the hexosamine biosynthesis pathway (HBP) to maintain tumour cell growth and survival. Here we investigated if short-term glucose deprivation specifically modulates the phosphatidylino... |
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Qualitative and quantitative determination of peptides related to celiac disease in mixtures derived from different methods of simulated gastrointestinal digestion of wheat products.
Anal. Bioanal. Chem 406(19) , 4765-75, (2014) During wheat digestion, gluten-derived proteolytic resistant peptides are generated, some of them involved in celiac disease. In vitro digestion models able to mimic the peptides generated in the human gastrointestinal tract are extremely useful to assess the... |
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The dissolution enhancement of piroxicam in its physical mixtures and solid dispersion formulations using gluconolactone and glucosamine hydrochloride as potential carriers.
Pharm. Dev. Technol. 20(1) , 74-83, (2015) The solid dispersion technique is one of the most effective methods for improving the dissolution rate of poorly water-soluble drugs; however this is reliant on a suitable carrier and solvent being selected. The work presented explores amino sugars (d-glucosa... |
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Identification of genes involved in biosynthesis of mannan polysaccharides in Dendrobium officinale by RNA-seq analysis.
Plant Mol. Biol. 88 , 219-31, (2015) Dendrobium officinale is a traditional Chinese medicinal plant. The stems of D. officinale contain mannan polysaccharides, which are promising bioactive polysaccharides for use as drugs. However, the genes involved in the biosynthesis of mannan polysaccharide... |
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Superresolved labeling nanoscopy based on temporally flickering nanoparticles and the K-factor image deshadowing.
Biomed. Opt. Express 6(4) , 1262-72, (2015) Localization microscopy provides valuable insights into cellular structures and is a rapidly developing field. The precision is mainly limited by additive noise and the requirement for single molecule imaging that dictates a low density of activated emitters ... |
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Studies on the Formation of Maillard and Caramelization Products from Glucosamine Incubated at 37 °C.
J. Agric. Food Chem. 63 , 6249-61, (2015) This experiment compared the in vitro degradation of glucosamine (GlcN), N-acetylglucosamine, and glucose in the presence of NH3 incubated at 37 °C in phosphate buffer from 0.5 to 12 days. The reactions were monitored with UV-vis absorption and fluorescence e... |
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Glucosamine-induced Sp1 O-GlcNAcylation ameliorates hypoxia-induced SGLT dysfunction in primary cultured renal proximal tubule cells.
J. Cell Physiol. 229(10) , 1557-68, (2014) The aim of this study is to determine whether GlcN could recover the endoplasmic reticulum (ER) stress-induced dysfunction of Na(+) /glucose cotransporter (SGLT) in renal proximal tubule cells (PTCs) under hypoxia. With the rabbit model, the renal ischemia in... |
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Poly (3-hydroxyalkanoates)-co-(6-hydroxyhexanoate) hydrogel promotes angiogenesis and collagen deposition during cutaneous wound healing in rats.
Biomed. Mater. 10 , 045001, (2015) Wound management and healing in several physiological or pathological conditions, particularly when comorbidities are involved, usually proves to be difficult. This presents complications leading to socio-economic and public health burdens. The accelerative w... |
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Preparation, physical–chemical and biological characterization of chitosan nanoparticles loaded with lysozyme
Int. J. Biol. Macromol. 67 , 124-31, (2014) A commercially available chitosan (CS) was employed in the formulation of nanoparticles loaded with lysozyme (LZ) as antimicrobial protein drug model. Due to the variability of commercially available batches of chitosans and to the strict dependence of their ... |
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Towards a full integration of optimization and validation phases: An analytical-quality-by-design approach
J. Chromatogr. A. 1395 , 88-98, (2015) • An enhanced quality-by-design strategy throughout the analytical method lifecycle. • Quantitative design space: an innovative approach for development of analytical methods. • Integrated approaches for optimization and validation phases. • Full validation o... |