Pterin-6-carboxylic acid

Pterin-6-carboxylic acid Structure
Pterin-6-carboxylic acid structure
Common Name Pterin-6-carboxylic acid
CAS Number 948-60-7 Molecular Weight 207.14600
Density 2.16 g/cm3 Boiling Point 608.7ºC at 760 mmHg
Molecular Formula C7H5N5O3 Melting Point N/A
MSDS USA Flash Point 322ºC

Photodegradation of folic acid in aqueous solution.

J. Pharm. Biomed. Anal. 19 , 269-275, (1999)

A study of the photodegradation of folic acid by ultraviolet radiation in aqueous solution has been made. Folic acid is photolysed by an apparent first-order kinetics and the log k-pH profile shows a gradual decrease in rate in the pH range 2.0-10.0. The prof...

Biosynthesis and metabolism of tetrahydrobiopterin and molybdopterin.

Annu. Rev. Biochem. 54 , 729, (1985)

5-Methyltetrahydrofolate inhibits photosensitization reactions and strand breaks in DNA.

FASEB J. 21 , 2101-2107, (2007)

The known functions of folate are to support one-carbon metabolism and to serve as photoreceptors for cryptochromes and photolyases. We demonstrate that 5-methyltetrahydrofolate (5-MTHF, the predominant folate in plasma) is also a potent, near diffusion limit...

Sequence-specific DNA damage induced by ultraviolet A-irradiated folic acid via its photolysis product.

Arch. Biochem. Biophys. 410 , 261-268, (2003)

DNA damage mediated by photosensitizers participates in solar carcinogenesis. Fluorescence measurement and high-performance liquid chromatography analysis demonstrated that photoirradiated folic acid, one of the photosensitizers in cells, generates pterine-6-...

Type I collagen as an extracellular matrix for the in vitro growth of human small intestinal epithelium.

J. Pharm. Biomed. Anal. 23 , 1039-1044, (2000)

We previously reported in vitro maintenance and proliferation of human small intestinal epithelium using Matrigel, a proprietary basement membrane product. There are concerns over the applicability of Matrigel-based methods for future human therapies. We inve...