2-Azahypoxanthine

2-Azahypoxanthine Structure
2-Azahypoxanthine structure
Common Name 2-Azahypoxanthine
CAS Number 4656-86-4 Molecular Weight 137.10000
Density 2.263g/cm3 Boiling Point 512.9ºC at 760 mmHg
Molecular Formula C4H3N5O Melting Point 264 °C
MSDS N/A Flash Point 264ºC

Role of tautomerism of 2-azaadenine and 2-azahypoxanthine in substrate recognition by xanthine oxidase.

J. Comput. Aided Mol. Des. 11(2) , 153-62, (1997)

The tautomerism of 2-azaadenine and 2-hypoxanthine has been examined in the gas phase and in aqueous solution. The tautomerism in the gas phase has been studied by means of semiempirical and ab initio quantum-mechanical computations, as well as density-functi...

Simultaneous determination of dacarbazine, its photolytic degradation product, 2-azahypoxanthine, and the metabolite 5-aminoimidazole-4-carboxamide in plasma and urine by high-pressure liquid chromatography.

Antimicrob. Agents Chemother. 27(6) , 977-9, (1985)

A high-pressure liquid chromatographic method has been developed that allows for the simultaneous analysis of dacarbazine (DTIC), 5-aminoimidazole-4-carboxamide (AIC), and 2-azahypoxanthine (2-AZA) in plasma or urine. Plasma samples were prepared by ultrafilt...

Metabolism and metabolic effects of 2-azahypoxanthine and 2-azaadenosine.

Biochem. Pharmacol. 34(8) , 1293-304, (1985)

The metabolism and metabolic effects of 2-azahypoxanthine and 2-azaadenosine were studied to elucidate the biochemical basis for their known cytotoxicities. 2-Azaadenosine is a known substrate for adenosine kinase. That 2-azahypoxanthine is a substrate for hy...

Disclosure of the "fairy" of fairy-ring-forming fungus Lepista sordida.

ChemBioChem. 11(10) , 1373-7, (2010)

Mechanisms of 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (Dacarbazine) cytotoxicity toward Chinese hamster ovary cells in vitro are dictated by incubation conditions.

Chem. Biol. Interact. 58(3) , 319-31, (1986)

Decomposition of the antitumor agent 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (DTIC, Dacarbazine) produces several potentially toxic compounds, the concentration of which depend on incubation parameters such as pH, temperature and illumination. The ...