Stearic acid amide

Stearic acid amide Structure
Stearic acid amide structure
Common Name Stearic acid amide
CAS Number 124-26-5 Molecular Weight 283.49200
Density 0.868 g/cm3 Boiling Point 250-251 °C12 mm Hg(lit.)
Molecular Formula C18H37NO Melting Point 98-102 °C(lit.)
MSDS Chinese USA Flash Point 207.5ºC

Development and validation of method for TH588 and TH287, potent MTH1 inhibitors and new anti-cancer agents, for pharmacokinetic studies in mice plasma.

J. Pharm. Biomed. Anal. 104 , 1-11, (2014)

MTH1 is a protein that is required for cancer cell survival and is overexpressed in cancer cells. TH588 and TH287 are two new compounds that inhibit the MTH1 protein. The inhibitors were tested in pharmacokinetic studies on mice. A bioanalytical method was de...