2-Naphthaldehyde
2-Naphthaldehyde structure
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Common Name | 2-Naphthaldehyde | ||
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| CAS Number | 66-99-9 | Molecular Weight | 156.181 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 299.5±9.0 °C at 760 mmHg | |
| Molecular Formula | C11H8O | Melting Point | 58-61 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 179.5±5.0 °C | |
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Studies on structure-activity relationship of gossypol, gossypol ethers and three naphthaldehydes in the inhibition of spermatozoal metabolism.
Contraception 33(5) , 519-28, (1986) Gossypol tetramethyl ether [C30 H24 O2(OCH3)4] and gossypol hexamethyl ether [C30 H24 O2(OCH3)6], which in contrast to gossypol are stable compounds, were tested for their ability to depress fructose degradation in fresh human sperm cells. Both ethers inhibit... |
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Naphthaldehydes as reversible inhibitors of rat hepatic aryl sulfotransferase IV (tyrosine-ester sulfotransferase).
Drug Metab. Dispos. 21(2) , 400-2, (1993)
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pH-Responsive polymeric micelles based on amphiphilic chitosan derivatives: Effect of hydrophobic cores on oral meloxicam delivery.
Int. J. Pharm. 497 , 150-60, (2016) The amphiphilic chitosan derivatives, N-naphthyl-N,O-succinyl chitosan (NSCS), N-octyl-N-O-succinyl chitosan (OSCS) and N-benzyl-N,O-succinyl chitosan (BSCS), were synthesized. Meloxicam (MX) was loaded into polymeric micelles (PMs), and the effects of hydrop... |
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Enantioselective Addition of Diethylzinc to Aldehydes Catalyzed by Chiral O,N,O-tridentate Phenol Ligands Derived From Camphor.
Chirality 28 , 65-71, (2016) Chiral O,N,O-tridentate phenol ligands bearing a camphor backbone were found to be effective chiral catalysts for the enantioselective addition of diethylzinc to aromatic aldehydes, resulting in high enantioselectivities (80-95% ee) at room temperature.© 2015... |
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A heptaketide naphthaldehyde produced by a polyketide synthase from Nectria haematococca.
Bioorg. Med. Chem. Lett. 22(13) , 4338-40, (2012) Bostrycoidin and fusarubin are biologically active fungal polyketides produced by Nectria haematococca. This azaanthraquinone and naphthoquinone are thought to be biosynthesized via formation of a C(14) heptaketide aldehyde as a common key intermediate. A BLA... |
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Induction of apoptosis and cell cycle arrest in L-1210 murine lymphoblastic leukaemia cells by (2E)-3-(2-naphthyl)-1-(3'-methoxy-4'-hydroxy-phenyl)-2-propen-1-one.
J. Pharm. Pharmacol. 62(9) , 1128-36, (2010) New compounds with biological targets and less cytotoxicity to normal cells are necessary for cancer therapy. In this work ten synthetic chalcones derived from 2-naphtaldehyde were evaluated for their cytotoxic effect in murine acute lymphoblastic leukemia ce... |
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Evaluation of alpha-cyano ethers as fluorescent substrates for assay of cytochrome P450 enzyme activity.
Anal. Biochem. 344(2) , 183-92, (2005) We have previously reported the synthesis of four alpha-cyano-containing ethers based on 2-naphthaldehyde (2-NA) as cytochrome P450 (P450) fluorescent substrates. Activity detection was based on the formation of fluorescent 2-NA following substrate hydrolysis... |
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Salivary aldehyde dehydrogenase: activity towards aromatic aldehydes and comparison with recombinant ALDH3A1.
Molecules 14(7) , 2363-72, (2009) A series of aromatic aldehydes was examined as substrates for salivary aldehyde dehydrogenase (sALDH) and the recombinant ALDH3A1. Para-substituted benzaldehydes, cinnamic aldehyde and 2-naphthaldehydes were found to be excellent substrates, and kinetic param... |