Rubusoside
Rubusoside structure
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Common Name | Rubusoside | ||
|---|---|---|---|---|
| CAS Number | 64849-39-4 | Molecular Weight | 642.732 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 802.5±65.0 °C at 760 mmHg | |
| Molecular Formula | C32H50O13 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 251.9±27.8 °C | |
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Cytotoxic and antiangiogenic paclitaxel solubilized and permeation-enhanced by natural product nanoparticles.
Anticancer Drugs 26(2) , 167-79, (2014) Paclitaxel (PTX) is one of the most potent intravenous chemotherapeutic agents to date, yet an oral formulation has been problematic because of its low solubility and permeability. Using the recently discovered solubilizing properties of rubusoside (RUB), we ... |
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[Identification and biotransformation properties of a bacterium that converts stevioside into rubusoside].
Wei Sheng Wu Xue Bao 51(1) , 43-9, (2011) The purpose of our study was to separate and identify a bacillus that could convert stevioside specifically. Then we identified the conversion product and studied the conversion capability of the bacillus. We also studied the enzyme with conversion capability... |
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[Study on quality control of Rubus suavissimus].
Zhong Yao Cai 31(11) , 1734-7, (2008) To control the quality of Rubus suavissimus.We inspected the character observation, microscopic, physical and chemical identification, TLC, the examination of water and extraction of Rubus suavissimus, then used HPLC to assay the contents of the principal swe... |
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Further study on the 1,4-alpha-transglucosylation of rubusoside, a sweet steviol-bisglucoside from Rubus suavissimus.
Agric. Biol. Chem. 55(2) , 449-53, (1991) Rubusoside (the beta-D-glucosyl ester of 13-O-beta-D-glucosyl-steviol), which is the major sweet principle of leaves of Rubus suavissimus S. Lee, was subjected to 1,4-alpha-transglucosylation by the cyclodextringlucanotransferase-starch system (the CGTase sys... |
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Mass spectral analysis of some derivatives and in vitro metabolites of steviol, the aglycone of the natural sweeteners, stevioside, rebaudioside A, and rubusoside.
Biomed. Environ. Mass Spectrom. 15(4) , 211-22, (1988) Steviol (ent-13-hydroxykaur-16-en-19-oic acid), the aglycone of various plant-derived glycoside sweeteners consumed by human populations, is known to be mutagenic toward Salmonella tymphimurium strain TM677 when metabolically activated using a 9000 x g supern... |
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Quantitative and fingerprint analyses of Chinese sweet tea plant ( Rubus suavissimus S. Lee).
J. Agric. Food Chem. 57(3) , 1076-83, (2009) The quality of botanical food is increasingly assessed by the content of multiple bioactive compounds. This study reports, for the first time, an HPLC fingerprinting method for the quality evaluation of Rubus suavissimus leaves possessing multiple bioactiviti... |
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A novel solubility-enhanced curcumin formulation showing stability and maintenance of anticancer activity.
J. Pharm. Sci. 100(7) , 2778-89, (2011) Curcumin (CUR) is an active food compound, but its insolubility and instability in water contributes to low bioavailability. In this study, the solubility of CUR was enhanced by utilizing the solubilizing properties of rubusoside (RUB). The solubility of CUR ... |
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Structures of the novel α-glucosyl linked diterpene glycosides from Stevia rebaudiana.
Carbohydr. Res. 346(13) , 2034-8, (2011) From the commercial extract of the leaves of Stevia rebaudiana, two new minor diterpene glycosides having α-glucosyl linkage were isolated besides the known steviol glycosides including stevioside, steviolbioside, rebaudiosides A-F, rubusoside and dulcoside A... |
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Mass production of rubusoside using a novel stevioside-specific β-glucosidase from Aspergillus aculeatus.
J. Agric. Food Chem. 60(24) , 6210-6, (2012) Rubusoside (R) is a natural sweetener and a solubilizing agent with antiangiogenic and antiallergic properties. However, currently, its production is quite expensive, and therefore, we have investigated nine commercially available glycosidases to optimize an ... |
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Reformulation of etoposide with solubility-enhancing rubusoside.
Int. J. Pharm. 434(1-2) , 453-9, (2012) Etoposide (ETO), a widely used anti-cancer drug, is constrained by its low aqueous solubility and by side effects from both the drug and its solubilizing excipients. In this study, a recently discovered natural solubilizer rubusoside (RUB) was used to achieve... |