Methyl (4-hydroxymethyl)benzoate

Methyl (4-hydroxymethyl)benzoate Structure
Methyl (4-hydroxymethyl)benzoate structure
Common Name Methyl (4-hydroxymethyl)benzoate
CAS Number 6908-41-4 Molecular Weight 166.17400
Density 1.177g/cm3 Boiling Point 157 °C / 5mmHg
Molecular Formula C9H10O3 Melting Point 47-50 °C(lit.)
MSDS Chinese USA Flash Point >230 °F

Evolution, synthesis and SAR of tripeptide alpha-ketoacid inhibitors of the hepatitis C virus NS3/NS4A serine protease.

Bioorg. Med. Chem. Lett. 12(4) , 705-8, (2002)

N-terminal truncation of the hexapeptide ketoacid 1 gave rise to potent tripeptide inhibitors of the hepatitis C virus NS3 protease/NS4A cofactor complex. Optimization of these tripeptides led to ketoacid 30 with an IC50 of 0.38 microM. The SAR of these tripe...