8-PIP-cAMP
8-PIP-cAMP structure
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Common Name | 8-PIP-cAMP | ||
|---|---|---|---|---|
| CAS Number | 31357-06-9 | Molecular Weight | 434.31900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H20N6NaO6P | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Cyclic AMP can promote APL progression and protect myeloid leukemia cells against anthracycline-induced apoptosis.
Cell Death Dis. 4 , e516, (2013) We show that cyclic AMP (cAMP) elevating agents protect blasts from patients with acute promyelocytic leukemia (APL) against death induced by first-line anti-leukemic anthracyclines like daunorubicin (DNR). The cAMP effect was reproduced in NB4 APL cells, and... |
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8-Chloro-cyclic AMP and protein kinase A I-selective cyclic AMP analogs inhibit cancer cell growth through different mechanisms.
PLoS ONE 6(6) , e20785, (2011) Cyclic AMP (cAMP) inhibits the proliferation of several tumor cells. We previously reported an antiproliferative effect of PKA I-selective cAMP analogs (8-PIP-cAMP and 8-HA-cAMP) on two human cancer cell lines of different origin. 8-Cl-cAMP, another cAMP anal... |
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