(Ile3)-Pressinoic acid
(Ile3)-Pressinoic acid structure
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Common Name | (Ile3)-Pressinoic acid | ||
|---|---|---|---|---|
| CAS Number | 34330-23-9 | Molecular Weight | 740.848 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 1326.4±65.0 °C at 760 mmHg | |
| Molecular Formula | C30H44N8O10S2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 756.0±34.3 °C | |
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The role of oxytocin release in the paraventricular nucleus in the control of maternal behaviour in the sheep.
J. Neuroendocrinol. 8 , 163, (1996) Oxytocin (OT) release within the brain is thought to play a major role in inducing maternal behaviour in a number of mammalian species but little is known about the sites of release which are important in this respect. We have investigated whether the paraven... |
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Prolactin-releasing activity of neurohypophysial hormones: structure-function relationship.
Endocrinology 134 , 114, (1994) Oxytocin (OT) and arginine vasopressin (AVP) have been reported to release PRL both in vivo and in vitro. The objectives of this study were 1) to compare the potencies of the PRL-releasing activities of OT and TRH using cultured anterior pituitary (AP) cells,... |
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Oxytocin-like peptide: a novel epitope colocalized with the FMRFamide-like peptide in the supernumerary neurons of the sex segmental ganglia of leeches--morphological and biochemical characterization; putative anti-diuretic function.
Brain Res. 601 , 173, (1993) A large number of oxytocin (OT)-like neurons were detected in the sex segmental ganglia (SG5, SG6) of three species of leeches belonging to different orders: Theromyzon tessulatum, Hirudo medicinalis and Erpobdella octoculata. In this latter species, an epito... |
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[Effect of arginine vasotocin, oxytocin and their fragments on the corticosterone content in the blood plasma of chickens of different ages].
Fiziol. Zh. SSSR Im. I. M. Sechenova 68(1) , 112-5, (1982) Administration of arginin-vasotocin, oxytocin and their fragments had no effect on corticosterone content in the blood plasma of 10-month chickens whereas in 20 and 30-day chickens arginin-vasotocin and its terminal fragment: amid of prolyl-arginil-glycil, co... |
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Hypothalamic oxytocin mediates adaptation mechanism against chronic stress in rats.
Am. J. Physiol. Gastrointest. Liver Physiol. 299(4) , G946-53, (2010) Accumulation of continuous life stress (chronic stress) often causes gastric symptoms. Although central oxytocin has antistress effects, the role of central oxytocin in stress-induced gastric dysmotility remains unknown. Solid gastric emptying was measured in... |
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Prolyl-leucyl-glycinamide shares some effects with oxytocin but decreases oxytocin levels.
Physiol. Behav. 83(3) , 475-81, (2004) Oxytocin treatment in rats induces long-lasting antistress and growth promoting effects. This study investigated whether prolyl-leucyl-glycinamide (PLG) (the c-terminal tripeptide of oxytocin) or tocinoic acid (the ring structure of oxytocin) could induce som... |
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Interaction of oxytocin with Ca2+: I. CD and fluorescence spectral characterization and comparison with vasopressin.
Biopolymers 40(5) , 433-43, (1996) Extracellular Ca2+ is required for the action of oxytocin and both the hormone and its receptor have binding sites for divalent metal cations. To characterize the cation-bound form of oxytocin, we monitored the binding of Ca2+ and Mg2+ to oxytocin as well as ... |
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Thiol-disulfide interchange in the tocinoic acid/glutathione system during freezing and drying.
J. Pharm. Sci. 99(12) , 4849-56, (2010) Thiol-disulfide interchange ("disulfide scrambling") is a common mechanism of covalent aggregation for protein drugs. Using tocinoic acid (cyclo-S-Cys-Tyr-Ile-Gln-Asn-Cys-(S); TA(ox)) and glutathione (γGlu-Cys-Gly; GSH), our previous work demonstrated that th... |
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Characterization of the thiol/disulfide chemistry of neurohypophyseal peptide hormones by high-performance liquid chromatography.
Anal. Chem. 65(21) , 3061-6, (1993) Methodology is described for characterization of the kinetics and equilibria of thiol/disulfide interchange reactions of the disulfide bonds in the neurohypophyseal peptide hormones arginine vasopressin and oxytocin and the related peptides pressinoic acid an... |
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Solid phase synthesis of partially protected tocinoic acid: optimization with respect to resin and protecting groups.
J. Pept. Sci. 7(7) , 349-57, (2001) A few solid phase and solution approaches of good repute were applied in parallel with the aim to provide optimized routes to Boc- and Fmoc-tocinoic acid (3a and 3c) and the corresponding Tyr(Bu(t)) derivatives (3b and 3d). Boc-tocinoic acid is known to coupl... |