2-(2-Ethoxyethoxy)ethanol
2-(2-Ethoxyethoxy)ethanol structure
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Common Name | 2-(2-Ethoxyethoxy)ethanol | ||
|---|---|---|---|---|
| CAS Number | 111-90-0 | Molecular Weight | 134.174 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 202.0±0.0 °C at 760 mmHg | |
| Molecular Formula | C6H14O3 | Melting Point | -80 °C | |
| MSDS | Chinese USA | Flash Point | 96.1±0.0 °C | |
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Effects of spray-drying and choice of solid carriers on concentrations of Labrasol® and Transcutol® in solid self-microemulsifying drug delivery systems (SMEDDS).
Molecules 18(1) , 545-60, (2013) Solid self-microemulsifying drug delivery systems (SMEDDS) have been used increasingly for improving the bioavailability of hydrophobic drugs. Labrasol® and Transcutol® are used widely as surfactant and solubilizer in the formulation of solid SMEDDS. We inves... |
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Development and evaluation of new microemulsion-based hydrogel formulations for topical delivery of fluconazole.
AAPS PharmSciTech 16 , 889-904, (2015) The aim of the present investigation was to develop and evaluate microemulsion-loaded hydrogels (MEHs) for the topical delivery of fluconazole (FZ). The solubility of FZ in oils, surfactants and cosurfactants was evaluated to identify the components of the mi... |
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Development of artemether-loaded nanostructured lipid carrier (NLC) formulation for topical application.
Int. J. Pharm. 477(1-2) , 208-17, (2014) NLC topical formulation as an alternative to oral and parenteral (IM) delivery of artemether (ART), a poorly water-soluble drug was designed. A Phospholipon 85G-modified Gelucire 43/01 based NLC formulation containing 75% Transcutol was chosen from DSC studie... |
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Fascaplysin induces caspase mediated crosstalk between apoptosis and autophagy through the inhibition of PI3K/AKT/mTOR signaling cascade in human leukemia HL-60 cells.
J. Cell. Biochem. 116(6) , 985-97, (2015) In this study, we for the first time explored the cellular and molecular mechanism of anticancer properties of fascaplysin, a marine sponge-derived alkaloid. Our study demonstrated that fascaplysin induced a cooperative interaction between apoptotic and autop... |
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Acid-responsive polymeric nanocarriers for topical adapalene delivery.
Pharm. Res. 31(11) , 3051-9, (2014) The acne skin is characteristic of a relatively lower pH microenvironment compared to the healthy skin. The aim of this work was to utilize such pH discrepancy as a site-specific trigger for on-demand topical adapalene delivery.The anti-acne agent, adapalene,... |
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Development of drug-in-adhesive patch formulations for transdermal delivery of fluoxetine: In vitro and in vivo evaluations.
Int. J. Pharm. 487 , 49-55, (2015) The aim of this study was to develop drug-in adhesive (DIA) patch formulations for the transdermal delivery of fluoxetine (FX). The DIA patch formulations containing FX were prepared and optimized with various pressure sensitive adhesives, drug contents and e... |
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Self-Assembled On-Chip-Integrated Giant Magneto-Impedance Sensorics.
Adv. Mater. 27 , 6582-9, (2015) A novel method relying on strain engineering to realize arrays of on-chip-integrated giant magneto-impedance (GMI) sensors equipped with pick-up coils is put forth. The geometrical transformation of an initially planar layout into a tubular 3D architecture st... |
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Formulation of microemulsion systems for dermal delivery of silymarin.
AAPS PharmSciTech 13(2) , 389-99, (2012) Silymarin is a standardized extract from Silybum marianum seeds, known for its many skin benefits such as antioxidant, anti-inflammatory, and immunomodulatory properties. In this study, the potential of several microemulsion formulations for dermal delivery o... |
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Expeditious low-temperature sintering of copper nanoparticles with thin defective carbon shells.
Nanoscale 7(15) , 6627-35, (2015) The realization of air-stable nanoparticles, well-formulated nanoinks, and conductive patterns based on copper is a great challenge in low-cost and large-area flexible printed electronics. This work reports the synthesis of a conductively interconnected coppe... |
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[Modelling of pecutaneous drug permeation and investigation of penetration enhancer effect].
Acta Pharm. Hung. 82(1) , 15-22, (2012) Present study provides a short review concerning the applicable membranes for modelling the percutaneous drug permeation and about their importance. The theoretical introduction summarizes the transdermal drug permeation routes and enhancement strategies. Two... |