Triethyl citrate
Triethyl citrate structure
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Common Name | Triethyl citrate | ||
|---|---|---|---|---|
| CAS Number | 77-93-0 | Molecular Weight | 276.283 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 294.0±0.0 °C at 760 mmHg | |
| Molecular Formula | C12H20O7 | Melting Point | -46 °C | |
| MSDS | Chinese USA | Flash Point | 95.4±11.7 °C | |
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Novel in situ gelling ocular films for the opioid growth factor-receptor antagonist-naltrexone hydrochloride: fabrication, mechanical properties, mucoadhesion, tolerability and stability studies.
Int. J. Pharm. 477(1-2) , 631-42, (2014) Naltrexone hydrochloride (NTX) is an innovative drug used in ophthalmology for treatment of ocular surface diseases such as impaired corneal wound healing and severe dry eye. Poor chemical stability has been a major limitation for development of NTX in soluti... |
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Formulation considerations in the design of topical, polymeric film-forming systems for sustained drug delivery to the skin.
Eur. J. Pharm. Biopharm. 91 , 9-15, (2015) Polymeric film-forming systems (FFSs) are potential drug delivery systems for topical application to the skin. The FFSs form thin and transparent polymeric films in situ upon solvent evaporation. Their application convenience and cosmetic attributes, superior... |
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Controlled release of acidic drugs in compendial and physiological hydrogen carbonate buffer from polymer blend-coated oral solid dosage forms.
Eur. J. Pharm. Sci. 77 , 246-53, (2015) The objective of this study was to investigate the suitability of "Eudragit® RL/Eudragit® L55" (RL/L55) blend coatings for a pH-independent release of acidic drugs. A coating for ketoprofen and naproxen mini tablets was developed showing constant drug release... |
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Influence of process and formulation parameters on dissolution and stability characteristics of Kollidon® VA 64 hot-melt extrudates.
AAPS PharmSciTech 16(2) , 444-54, (2015) The objective of the present study was to investigate the effects of processing variables and formulation factors on the characteristics of hot-melt extrudates containing a copolymer (Kollidon® VA 64). Nifedipine was used as a model drug in all of the extruda... |
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Preparation and evaluation of enteric-coated delayed-release pellets of duloxetine hydrochloride using a fluidized bed coater.
Arch. Pharm. Res. 38 , 2163-71, (2015) In this study, the enteric-coated delayed-release pellets of duloxetine hydrochloride (DLX) were formulated using a fluidized bed coater. Three separate layers, the drug layer, the barrier layer, and the enteric layer, were coated onto inert core pellets. Amo... |
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Formulation and characterization of ORMOSIL particles loaded with budesonide for local colonic delivery.
Int. J. Pharm. 484(1-2) , 75-84, (2015) In this study, hybrid silica xerogel particles were developed as carriers of budesonide (BDS) for efficient local treatment of inflammatory bowel diseases (IBD). Organically modified silica particles (ORMOSILs) were prepared by co-condensation of 3-aminopropy... |
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Preparation of amorphous solid dispersions by rotary evaporation and KinetiSol Dispersing: approaches to enhance solubility of a poorly water-soluble gum extract.
Drug Dev. Ind. Pharm. 41(3) , 382-97, (2015) Acetyl-11-keto-β-boswellic acid (AKBA), a gum resin extract, possesses poor water-solubility that limits bioavailability and a high melting point making it difficult to successfully process into solid dispersions by fusion methods. The purpose of this study w... |
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In-line spatial filtering velocimetry for particle size and film thickness determination in fluidized-bed pellet coating processes.
Eur. J. Pharm. Biopharm. 88(3) , 931-8, (2015) A spatial filtering velocimetry (SFV) probe was applied to monitor the increase in particle size during pellet Wurster coating processes in-line. Accuracy of the in-line obtained pellet sizes was proven by at-line performed digital image analysis (DIA). Regar... |
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Mini-tablets versus pellets as promising multiparticulate modified release delivery systems for highly soluble drugs.
Int. J. Pharm. 488 , 86-94, (2015) Whether mini-tablets (tablets, diameters ≤6mm) belong to single- or multiple-unit dosage forms is still questionable. Accordingly, Pharmacopoeial evaluation procedures for mini-tablets are lacking. In this study, the aforementioned points were discussed. More... |
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Intestinal pregnane X receptor links xenobiotic exposure and hypercholesterolemia.
Mol. Endocrinol. 29 , 765-76, (2015) Recent studies have associated endocrine-disrupting chemical (EDC) exposure with the increased risk of cardiovascular disease in humans, but the underlying mechanisms responsible for these associations remain elusive. Many EDCs have been implicated in activat... |