2'-Fucosyllactose
2'-Fucosyllactose structure
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Common Name | 2'-Fucosyllactose | ||
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| CAS Number | 41263-94-9 | Molecular Weight | 488.43800 | |
| Density | 1.68g/cm3 | Boiling Point | 902.2ºC at 760 mmHg | |
| Molecular Formula | C18H32O15 | Melting Point | 230-231 °C | |
| MSDS | Chinese USA | Flash Point | 311.9ºC | |
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[Studies of oligosaccharide specificity of perch roe fucolectin, using gold labeled neoglycoproteins].
Prikl. Biokhim. Mikrobiol. 39 , 105-109, (2003) The specificity of perch (Perca fluviatilis) roe fucolectin was studied using the protein dot blot technique, followed by detection with colloidal gold-labeled neoglycoproteins bearing human milk polysaccharides. The strongest binding was noted with the H typ... |
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Human milk oligosaccharides influence maturation of human intestinal Caco-2Bbe and HT-29 cell lines.
J. Nutr. 144(5) , 586-91, (2014) Stimulation of gastrointestinal tract maturation is 1 of the many benefits of human milk. Human milk oligosaccharides (HMOs) are abundant in human milk and are reported to promote enterocyte differentiation in vitro. The objective of this study was to assess ... |
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Lacto-N-tetraose, fucosylation, and secretor status are highly variable in human milk oligosaccharides from women delivering preterm.
J. Proteome Res. 11(9) , 4662-72, (2012) Breast milk is the ideal nutrition for term infants but must be supplemented to provide adequate growth for most premature infants. Human milk oligosaccharides (HMOs) are remarkably abundant and diverse in breast milk and yet provide no nutritive value to the... |
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Selective proliferation of intestinal Barnesiella under fucosyllactose supplementation in mice.
Br. J. Nutr. 111(9) , 1602-10, (2014) The oligosaccharides 2-fucosyllactose and 3-fucosyllactose are major constituents of human breast milk but are not found in mouse milk. Milk oligosaccharides have a prebiotic action, thus affecting the colonisation of the infant intestine by microbiota. To de... |
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Whole cell biosynthesis of a functional oligosaccharide, 2'-fucosyllactose, using engineered Escherichia coli.
Microb. Cell Fact. 11 , 48, (2012) 2'-Fucosyllactose (2-FL) is a functional oligosaccharide present in human milk which protects against the infection of enteric pathogens. Because 2-FL can be synthesized through the enzymatic fucosylation of lactose with guanosine 5'-diphosphate (GDP)-l-fucos... |
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Isolation and characterization from porcine serum of a soluble sulfotransferase responsible for 6-O-sulfation of the galactose residue in 2'-fucosyllactose: implications in the synthesis of the ligand for L-selectin.
Glycoconj. J. 16(7) , 357-63, (1999) A soluble sulfotransferase from porcine serum which catalyzes the transfer of sulfate from adenosine 3'-phosphate 5'-phosphosulphate (PAPS) to 2'-fucosyllactose (2'-FL) was purified 36,333-fold using a combination of conventional and affinity chromatographic ... |
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The human milk metabolome reveals diverse oligosaccharide profiles.
J. Nutr. 143(11) , 1709-18, (2013) Breast milk delivers nutrition and protection to the developing infant. There has been considerable research on the high-molecular-weight milk components; however, low-molecular-weight metabolites have received less attention. To determine the effect of mater... |
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The principal fucosylated oligosaccharides of human milk exhibit prebiotic properties on cultured infant microbiota.
Glycobiology 23(2) , 169-77, (2013) Breast-fed infant microbiota is typically rich in bifidobacteria. Herein, major human milk oligosaccharides (HMOS) are assessed for their ability to promote the growth of bifidobacteria and to acidify their environment, key features of prebiotics. During in v... |
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High-resolution crystal structures of Erythrina cristagalli lectin in complex with lactose and 2'-alpha-L-fucosyllactose and correlation with thermodynamic binding data.
J. Mol. Biol. 321(1) , 69-83, (2002) The primary sequence of Erythrina cristagalli lectin (ECL) was mapped by mass spectrometry, and the crystal structures of the lectin in complex with lactose and 2'-alpha-L-fucosyllactose were determined at 1.6A and 1.7A resolution, respectively. The two compl... |
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Improved method for the isolation of 2' fucosyllactose from human milk.
J. Chromatogr. A. 211(1) , 170-4, (1981)
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