N-(2-HYDROXYPROPYL)METHACRYLAMIDE
N-(2-HYDROXYPROPYL)METHACRYLAMIDE structure
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Common Name | N-(2-HYDROXYPROPYL)METHACRYLAMIDE | ||
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| CAS Number | 21442-01-3 | Molecular Weight | 143.18400 | |
| Density | 1.002g/cm3 | Boiling Point | 321.2ºC at 760mmHg | |
| Molecular Formula | C7H13NO2 | Melting Point | 70 °C | |
| MSDS | Chinese USA | Flash Point | 148.1ºC | |
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The influence of linker length on the properties of cathepsin S cleavable177Lu-labeled HPMA copolymers for pancreatic cancer imaging
Biomaterials 35(22) , 5760-70, (2014) N-(2-hydroxypropyl)-methacrylamide (HPMA) copolymers have shown promise for application in the detection and staging of cancer. However, non-target accumulation, particularly in the liver and spleen, hinders the detection of resident or nearby metastatic lesi... |
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Enhanced transcellular penetration and drug delivery by crosslinked polymeric micelles into pancreatic multicellular tumor spheroids.
Biomater. Sci. 3 , 1085-95, (2015) Many attempts have been made in the application of multicellular tumor spheroids (MCTS) as a 3D tumor model to investigate their biological responses upon introduction of polymeric micelles as nanocarriers for therapeutic applications. However, the micelle pe... |
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Vesicular glutamate transporter expression level affects synaptic vesicle release probability at hippocampal synapses in culture.
J. Neurosci. 34(35) , 11781-91, (2014) The vesicular glutamate transporter (VGLUT) plays an essential role in synaptic transmission by filling vesicles with glutamate. At mammalian synapses, VGLUT expression level determines the amount of glutamate packaged into vesicles, and the specific paralog ... |
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HPMA copolymers: origins, early developments, present, and future.
Adv. Drug Deliv. Rev. 62 , 122-149, (2010) The overview covers the discovery of N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers, initial studies on their synthesis, evaluation of biological properties, and explorations of their potential as carriers of biologically active compounds in general and ... |