phe-ala-ala-p-nitro-phe-phe-val-leu 4-pyridylmethyl ester

phe-ala-ala-p-nitro-phe-phe-val-leu 4-pyridylmethyl ester Structure
phe-ala-ala-p-nitro-phe-phe-val-leu 4-pyridylmethyl ester structure
Common Name phe-ala-ala-p-nitro-phe-phe-val-leu 4-pyridylmethyl ester
CAS Number 115389-04-3 Molecular Weight 950.09000
Density N/A Boiling Point N/A
Molecular Formula C50H63N9O10 Melting Point N/A
MSDS Chinese USA Flash Point N/A

An improved cathepsin-D substrate and assay procedure.

Anal. Biochem. 130 , 158, (1983)

Ten analogs of the peptide A-Phe(NO2)-Phe-Val-Leu-B were synthesized and tested as substrates for cathepsin D and pepsin. The best substrate found for cathepsin D, Phe-Ala-Ala-Phe(NO2)-Phe-Val-Leu-OM4P (kcat = 2.9 s-1; Km = 7.1 microM), has the largest kcat/K...