![]() docosanoic acid tryptamide structure
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Common Name | docosanoic acid tryptamide | ||
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CAS Number | 7367-79-5 | Molecular Weight | 482.78400 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C32H54N2O | Melting Point | 116-120ºC | |
MSDS | Chinese USA | Flash Point | N/A |
Neuropeptide Y in the noradrenergic neurones induces obesity and inhibits sympathetic tone in mice.
Acta Physiol. (Oxf.) 213(4) , 902-19, (2015) Neuropeptide Y (NPY) co-localized with noradrenaline in central and sympathetic nervous systems seems to play a role in the control of energy metabolism. In this study, the aim was to elucidate the effects and pathophysiological mechanisms of increased NPY in... |
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Effects of maternal nicotine exposure on thyroid hormone metabolism and function in adult rat progeny.
J. Endocrinol. 224(3) , 315-25, (2015) Postnatal nicotine exposure leads to obesity and hypothyroidism in adulthood. We studied the effects of maternal nicotine exposure during lactation on thyroid hormone (TH) metabolism and function in adult offspring. Lactating rats received implants of osmotic... |
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Glucose intolerance in aging male IGFBP-3 transgenic mice: differential effects of human IGFBP-3 and its mutant IGFBP-3 devoid of IGF binding ability.
Endocrinology 156(2) , 462-74, (2015) We have reported a reduction of insulin secretion and glucose intolerance in young mice overexpressing human IGFBP-3 (phosphoglycerate kinase [PGK]BP3) or its mutant Gly56/Gly80/Gly81-IGFBP-3 (PGKmutBP3) under the PGK promoter. Here, we investigated changes i... |
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A novel peripheral cannabinoid receptor 1 antagonist, BPR0912, reduces weight independently of food intake and modulates thermogenesis.
Diabetes Obes. Metab. 17(5) , 495-504, (2015) To investigate the in vivo metabolic effects of treatment with BPR0912, a novel and potent peripheral cannabinoid receptor 1 (CB1R) antagonist, on both normal mice and diet-induced obese (DIO) mice.The acute peripheral effects of BPR0912 administration on gas... |
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Distinct parameters of the basophil activation test reflect the severity and threshold of allergic reactions to peanut.
J. Allergy Clin. Immunol. 135(1) , 179-86, (2015) The management of peanut allergy relies on allergen avoidance and epinephrine autoinjector for rescue treatment in patients at risk of anaphylaxis. Biomarkers of severity and threshold of allergic reactions to peanut could significantly improve the care for p... |
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Gender-related effects on substrate utilization and metabolic adaptation in hairless spontaneously hypertensive rat.
Physiol. Res. 64(1) , 51-60, (2015) Cold exposure of rats leads to ameliorated glucose and triglyceride utilization with females displaying better adaptation to a cold environment. In the current study, we used hairless rats as a model of increased thermogenesis and analyzed gender-related effe... |
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Estrogens increase expression of bone morphogenetic protein 8b in brown adipose tissue of mice.
Biol. Sex. Differ. 6 , 7, (2015) In mammals, white adipose tissue (WAT) stores fat and brown adipose tissue (BAT) dissipates fat to produce heat. Several studies showed that females have more active BAT. Members of the bone morphogenetic protein (BMP) and fibroblast growth factor (FGF) famil... |
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Brown adipose tissue harbors a distinct sub-population of regulatory T cells.
PLoS ONE 10(2) , e0118534, (2015) Regulatory T (Treg) cells are critical determinants of both immune responses and metabolic control. Here we show that systemic ablation of Treg cells compromised the adaptation of whole-body energy expenditure to cold exposure, correlating with impairment in ... |
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BMP7 drives human adipogenic stem cells into metabolically active beige adipocytes.
Lipids 50(2) , 111-20, (2015) Adult humans have a substantial amount of inducible-brown (or beige) fat, which is associated with increased energy expenditure and reduced weight gain via thermogenesis. Despite the identification of key regulators of beige adipogenesis, impacts of dietary f... |
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Chemical modification of peanut conglutin reduces IgE reactivity but not T cell reactivity in peanut-allergic patients.
Clin. Exp. Allergy 44(12) , 1558-66, (2014) Specific immunotherapy for peanut allergy is associated with significant side-effects. Chemically modified allergens may provide a safer alternative.This study aimed to analyse the immunogenicity and allergenicity of modified peanut conglutin.Native peanut co... |