DL-Carnitine hydrochloride
DL-Carnitine hydrochloride structure
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Common Name | DL-Carnitine hydrochloride | ||
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| CAS Number | 461-05-2 | Molecular Weight | 197.660 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C7H16ClNO3 | Melting Point | 190-205ºC | |
| MSDS | USA | Flash Point | N/A | |
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Fenofibrate causes elevation of betaine excretion but not excretion of other osmolytes by healthy adults.
J. Clin. Lipidol. 8(4) , 433-40, (2014) Cross-sectional data suggest that bezafibrate increases betaine excretion in dyslipidemic patients.We aimed to demonstrate that fenofibrate induces increased betaine excretion in normal subjects and explore whether other 1-carbon metabolites and osmolytes are... |
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Extreme urinary betaine losses in type 2 diabetes combined with bezafibrate treatment are associated with losses of dimethylglycine and choline but not with increased losses of other osmolytes.
Cardiovasc. Drugs Ther. 28(5) , 459-68, (2014) Betaine deficiency is a probable cardiovascular risk factor and a cause of elevated homocysteine. Urinary betaine excretion is increased by fibrate treatment, and is also often elevated in diabetes. Does fibrate further increase betaine excretion in diabetes,... |
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Carnitine transporter CT2 (SLC22A16) is over-expressed in acute myeloid leukemia (AML) and target knockdown reduces growth and viability of AML cells.
Apoptosis 20 , 1099-108, (2015) AML (acute myeloid leukemia) cells have a unique reliance on mitochondrial metabolism and fatty acid oxidation (FAO). Thus, blocking FAO is a potential therapeutic strategy to target these malignant cells. In the current study, we assessed plasma membrane car... |
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Endogenous functional compounds in Korean native chicken meat are dependent on sex, thermal processing and meat cut.
J. Sci. Food Agric. 95(4) , 771-5, (2015) In this study the effects of sex, meat cut and thermal processing on the carnosine, anserine, creatine, betaine and carnitine contents of Korean native chicken (KNC) meat were determined. Forty 1-day-old chicks (20 chicks of each sex) from a commercial KNC st... |
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[Comparative evaluation of the effects of carnitine stereoisomers and racemate on the cardio- and hemodynamics of rats on a carnitine-deficient diet].
Vestn. Ross. Akad. Med. Nauk 7 , 20-27, (2006) L-carnitine (L-beta-hydroxy-gamma-N,N,N-trimethylaminobutyric acid) is conditionally necessary for mitochondrial transport and metabolism of long-chain fatty acids, and thus for myocardial energetic metabolism. D-carnitine is not biologically active and might... |
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[Stereopharmacology of carnitine].
Ross. Fiziol. Zh. Im. I. M. Sechenova 91 , 1469-1480, (2005) L-Carnitine (L-beta-hydroxy-gamma-N,N,N-trimethylaminobutyric acid) plays an essential role in fatty acid transport in the mitochondrion. Conditions that appear to benefit from exogenous supplementation of L-carnitine include anorexia, chronic fatigue, cardio... |
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Effects of L-, D-, and DL-carnitine on morphometric parameters of skeletal muscle and exercise performance of laboratory animals receiving carnitine-deficient diet.
Bull. Exp. Biol. Med. 142 , 458-460, (2006) Serum concentration of L-carnitine, the mean thickness of the skeletal muscle fiber, and exercise performance in the forced swimming test decreased in rats receiving a carnitine-deficient diet. Treatment with L-carnitine compensated for carnitine deficiency, ... |