β-Endorphin (30-31) (human)
β-Endorphin (30-31) (human) structure
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Common Name | β-Endorphin (30-31) (human) | ||
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| CAS Number | 7412-78-4 | Molecular Weight | 204.181 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 536.6±50.0 °C at 760 mmHg | |
| Molecular Formula | C7H12N2O5 | Melting Point | 155-158ºC (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 278.3±30.1 °C | |
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Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.
Nat. Chem. Biol. 5 , 45-52, (2009) Transporter-related nutrient sensors, called transceptors, mediate nutrient activation of signaling pathways through the plasma membrane. The mechanism of action of transporting and nontransporting transceptors is unknown. We have screened 319 amino acid anal... |
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Human PEPT1 pharmacophore distinguishes between dipeptide transport and binding.
J. Med. Chem. 49 , 3636-44, (2006) The human intestinal oligopeptide transporter (PEPT1) facilitates the absorption of dipeptides, tripeptides, and many peptidomimetic drugs. In this study, a large number of peptides were selected to investigate the structural features required for PEPT1 trans... |
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Angiotensin-I-converting enzyme inhibitory peptides: Chemical feature based pharmacophore generation
Eur. J. Med. Chem. 46 , 3428-33, (2011) A validated 3D pharmacophore model was generated for a series of ACE inhibitory peptides, which consisted of five features (two hydrophobic functions, two hydrogen bond acceptors, and a negative ionizable function). The built model was able to correctly predi... |
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Glycyl-L-glutamine, a precursor, and glycyl-L-glutamic acid, a neurotrophic factor for maintenance of acetylcholinesterase and butyrylcholinesterase in the preganglionically denervated superior cervical ganglion of the cat in vivo.
Proc. Natl. Acad. Sci. U. S. A. 82 , 5213, (1985) L. W. Haynes and M. E. Smith have reported [(1985) Biochem. Soc. Trans. 13, 174-175] that glycyl-L-glutamine (Gly-Gln) increases the A12 and G4 forms of acetylcholinesterase (AcChoEase) in cultured embryonic rat skeletal muscle. Since Gly-Gln meets the criter... |
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A three amino acid peptide, Gly-Pro-Arg, protects and rescues cell death induced by amyloid beta-peptide.
Exp. Neurol. 184(2) , 923-9, (2003) Amyloid beta-peptide (Abeta) contributes to the pathogenesis of Alzheimer's disease (AD), causing neuronal death through apoptosis. In this study, the neuroprotective role of small peptides, Gly-Pro-Glu (GPE), Gly-Glu (GE), Gly-Pro-Asp (GPD), and Gly-Pro-Arg ... |
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Cerebrospinal and plasma amino acid concentrations after administration of i.v. glycyl-glutamine and glycyl-tyrosine containing amino acid solutions in humans.
J. Parenter. Enteral Nutr. 20(4) , 281-6, (1996) Glycyl-glutamine and glycyl-tyrosine may supply adequate glutamine and tyrosine in amino acid solutions for parenteral nutrition. However, plasma peptides may be transported into the cerebrospinal fluid, exerting effects on the neuronal tissue. Cerebrospinal ... |
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Chiral separation of amino acids and glycyl dipeptides by chiral ligand-exchange capillary electrophoresis comparing Cu(II), Co(II), Ni(II) and Zn(II) complexes of three different sugar acids.
J. Chromatogr. A. 1204 , 210-218, (2008) This paper deals with comparative studies on the use of copper(II), cobalt(II), nickel(II) and zinc(II) complexes of d-gluconic acid, d-saccharic acid and l-threonic acid as chiral selectors for the enantioseparation of aromatic amino acids and glycyl dipepti... |
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Enantioseparation of glycyl-dipeptides by CEC using particle-loaded monoliths prepared by ring-opening metathesis polymerization (ROMP).
J. Biochem. Biophys. Methods 69 , 67-77, (2006) Novel particle-loaded monolithic capillary electrochromatography (CEC) phases for chiral separations were prepared via ring-opening metathesis polymerization (ROMP) within the confines of fused silica columns with 200 microm i.d. using norborn-2-ene (NBE), 1,... |
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Enantioseparation of dipeptides and tripeptides by micro-HPLC comparing teicoplanin and teicoplanin aglycone as chiral selectors.
J. Biochem. Biophys. Methods 61 , 1-10, (2004) Chiral separation of glycyl- and diastereomeric dipeptides and tripeptides was performed by micro-HPLC using macrocyclic antibiotics as chiral selectors. Teicoplanin was compared with teicoplanin aglycone (TAG) regarding selectivity, efficiency and separation... |
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Fast chiral separation by ligand-exchange HPLC using a dynamically coated monolithic column.
J. Sep. Sci. 29 , 1470, (2006) The preparation and application of dynamically coated ligand-exchange chromatography phases for enantioseparation is described. The phases were prepared by pumping a solution of N-decyl-L-4-hydroxyproline, N-hexadecyl-L-4-hydroxyproline, or N-2-hydroxydodecyl... |