SB-668875

SB-668875 Structure
SB-668875 structure
Common Name SB-668875
CAS Number 274252-40-3 Molecular Weight 2857.26
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C120H206N44O35S Melting Point N/A
MSDS USA Flash Point N/A

Pharmacological characterisation of the orexin receptor subtype mediating postsynaptic excitation in the rat dorsal raphe nucleus.

Neuropharmacology 46 , 1168-1176, (2004)

Electrophysiological recordings from dorsal raphe nucleus (DRN) neurones in rat brain slices have revealed that the orexins can cause direct and reversible depolarisation of the postsynaptic membrane. Whilst it is known that the membrane depolarisation produc...