polydeoxyguanylic-deoxy-cytidylic acid sodium salt

polydeoxyguanylic-deoxy-cytidylic acid sodium salt Structure
polydeoxyguanylic-deoxy-cytidylic acid sodium salt structure
Common Name polydeoxyguanylic-deoxy-cytidylic acid sodium salt
CAS Number 90385-88-9 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS USA Flash Point N/A

Repression of arterial genes in hemogenic endothelium is sufficient for haematopoietic fate acquisition.

Nat. Commun. 6 , 7739, (2015)

Changes in cell fate and identity are essential for endothelial-to-haematopoietic transition (EHT), an embryonic process that generates the first adult populations of haematopoietic stem cells (HSCs) from hemogenic endothelial cells. Dissecting EHT regulation...

Is photocleavage of DNA by YOYO-1 using a synchrotron radiation light source sequence dependent?

Eur. Biophys. J. 40 , 1121-1129, (2011)

The photocleavage of double-stranded and single-stranded DNA by the fluorescent dye YOYO-1 was investigated in real time by using the synchrotron radiation light source ASTRID (ISA, Denmark) both to initiate the reaction and to monitor its progress using Coue...

DNA excited-state dynamics: from single bases to the double helix.

Annu. Rev. Phys. Chem. 60 , 217-239, (2009)

Ultraviolet light is strongly absorbed by DNA, producing excited electronic states that sometimes initiate damaging photochemical reactions. Fully mapping the reactive and nonreactive decay pathways available to excited electronic states in DNA is a decades-o...

Homogeneous assay based on anti-Stokes' shift time-resolved fluorescence resonance energy-transfer measurement.

Anal. Chem. 77 , 1483-1487, (2005)

We report here a novel, time-resolved, lanthanide-based energy-transfer assay utilizing nonoverlapping acceptor fluorophores, which have their absorption energetically at a higher level than the emittive transitions of the donor. The technique was studied by ...

Role of excited states in low-energy electron (LEE) induced strand breaks in DNA model systems: influence of aqueous environment.

ChemPhysChem 10 , 1426-1430, (2009)

Low-energy electrons (LEEs) interact with a DNA model system to create a variety of excited states. In the gas phase, dissociative (sigma*) states are accessible by LEEs with energy <4 eV (see picture) and cause facile strand breaks through a dissociative ele...

Effect of the alkaline cations on the stability of the model polynucleotide poly(dG-dC)·poly(dG-dC).

J. Biomol. Struct. Dyn. 29 , 585-594, (2011)

When the model polynucleotide poly(dG-dC)∙poly(dG-dC) [polyGC] is titrated with a strong acid (HCl) in unbuffered aqueous solutions containing the chlorides of the alkali metals in the concentration range 0.010 M-0.600 M, two transitions in the absorbance vs....

[Cu(o-phthalate)(phenanthroline)] Exhibits Unique Superoxide-Mediated NCI-60 Chemotherapeutic Action through Genomic DNA Damage and Mitochondrial Dysfunction.

ACS Chem. Biol. 11 , 159-71, (2016)

The in cellulo catalytic production of reactive oxygen species (ROS) by copper(II) and iron(II) complexes is now recognized as a major mechanistic model in the design of effective cytotoxins of human cancer. The developmental complex, [Cu(o-phthalate)(1,10-ph...