Polymyxin deacylase

Polymyxin deacylase Structure
Polymyxin deacylase structure
Common Name Polymyxin deacylase
CAS Number 111174-43-7 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS USA Flash Point N/A

Determination of N-myristoyl peptide sequence both by MALDI TOF MASS and with an N-myristoyl cleaving enzyme (polymyxin acylase).

Biochem. Biophys. Res. Commun. 217 , 632-639, (1995)

Polymyxin acylase isolated from Pseudomonas sp. M-6-3 was used as an N-myristoyl cleaving enzyme in order to determine a part of the N-terminal amino acid sequence of N-myristoyl proteins. The enzyme hydrolyzed a number of N-myristoyl oligopeptides at various...

In vitro antitumor activity of polymyxin acylase from Pseudomonas sp. M-6-3.

Biol. Pharm. Bull. 18 , 615-617, (1995)

Polymyxin acylase from Pseudomonas sp. M-6-3 can deacylate not only polymyxin group antibiotics, but also the long-chain fatty acyl group of proteins and peptides. We found the in vitro antitumor activity of polymyxin acylase against murine and human tumor ce...