Diacetyldichlorofluorescein
Diacetyldichlorofluorescein structure
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Common Name | Diacetyldichlorofluorescein | ||
|---|---|---|---|---|
| CAS Number | 2044-85-1 | Molecular Weight | 485.27000 | |
| Density | 1.59 g/cm3 | Boiling Point | 657.9ºC at 760 mmHg | |
| Molecular Formula | C24H14Cl2O7 | Melting Point | 232-234ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 239.2ºC | |
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Chronic low level arsenic exposure evokes inflammatory responses and DNA damage.
Int. J. Hyg. Environ. Health 218 , 564-74, (2015) The cross-sectional study investigated the impact of chronic low level arsenic (As) exposure (11-50μg/L) on CD14 expression and other inflammatory responses in rural women of West Bengal enrolled from control (As level <10μg/L; N, 131) and exposed area (As le... |
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JNK suppression of chemotherapeutic agents-induced ROS confers chemoresistance on pancreatic cancer stem cells.
Oncotarget 6(1) , 458-70, (2015) Chemoresistance associated with cancer stem cells (CSCs), which is now being held responsible for the pervasive therapy resistance of pancreatic cancer, poses a major challenge to the successful management of this devastating malignancy. However, the molecula... |
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NADPH oxidase mediated maneb- and paraquat-induced oxidative stress in rat polymorphs: Crosstalk with mitochondrial dysfunction.
Pestic. Biochem. Physiol. 123 , 74-86, (2015) Oxidative stress is a key factor in Parkinson's disease (PD) pathogenesis. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and impaired mitochondrion regulate oxidative stress-mediated maneb (MB)- and paraquat (PQ)-induced Parkinsonism. However, t... |
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Redox effects and cytotoxic profiles of MJ25 and auranofin towards malignant melanoma cells.
Oncotarget 6 , 16488-506, (2015) Malignant melanoma is the most dangerous type of skin cancer. Although recent progress in treatment has been achieved, lack of response, drug resistance and relapse remain major problems. The tumor suppressor p53 is rarely mutated in melanoma, yet it is inact... |
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Remarkable enhancement in photocytotoxicity and hydrolytic stability of curcumin on binding to an oxovanadium(IV) moiety.
Dalton Trans. 44(9) , 4108-22, (2015) Oxovanadium(IV) complexes of polypyridyl and curcumin-based ligands, viz. [VO(cur)(L)Cl] (1, 2) and [VO(scur)(L)Cl] (3, 4), where L is 1,10-phenanthroline (phen in 1 and 3), dipyrido[3,2-a:2',3'-c]phenazine (dppz in 2 and 4), Hcur is curcumin and Hscur is dig... |
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Investigation on cellular interactions of astrocytes with zinc oxide nanoparticles using rat C6 cell lines.
Colloids Surf. B Biointerfaces 133 , 1-11, (2015) Zinc oxide nanoparticles (ZnO NPs) are widely used in cosmetic industries and have also found important applications in electrical and chemical industries. It is well documented that inhaled ZnO NPs can reach the brain through the olfactory neuronal pathway a... |
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Gossypetin ameliorates ionizing radiation-induced oxidative stress in mice liver--a molecular approach.
Free Radic. Res. 49 , 1173-86, (2015) Radioprotective action of gossypetin (GTIN) against gamma (γ)-radiation-induced oxidative stress in liver was explored in the present article. Our main aim was to evaluate the protective efficacy of GTIN against radiation-induced alteration of liver in murine... |
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All-trans retinoic acid prevents oxidative stress-induced loss of renal tight junction proteins in type-1 diabetic model.
J. Nutr. Biochem. 26 , 441-54, (2015) We previously reported that diabetes decreased the expression of renal tight junction (TJ) proteins claudin-5 in glomerulus, and claudin-2 and occludin in proximal tubule through an oxidative stress dependent way. Now we investigated whether all-trans retinoi... |
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Synthetic ion transporters can induce apoptosis by facilitating chloride anion transport into cells.
Nature Chemistry 6(10) , 885-92, (2014) Anion transporters based on small molecules have received attention as therapeutic agents because of their potential to disrupt cellular ion homeostasis. However, a direct correlation between a change in cellular chloride anion concentration and cytotoxicity ... |
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Nanoparticle and polysaccharide conjugate: a potential candidate vaccine to improve immunological stimuli.
Int. J. Biol. Macromol. 72 , 1254-64, (2014) Active polysaccharides isolated from various fungal sources have been implicated to stimulate immune response against various pathogens as well as self anomalies such as cancer. Therefore, the nuanced approach presented in our work was to blend polysaccharide... |