Aluminium hydroxide

Aluminium hydroxide Structure
Aluminium hydroxide structure
Common Name Aluminium hydroxide
CAS Number 21645-51-2 Molecular Weight 78.004
Density 2.40 Boiling Point N/A
Molecular Formula Al(OH)3 Melting Point 300℃
MSDS Chinese USA Flash Point N/A

Tailoring subunit vaccine immunity with adjuvant combinations and delivery routes using the Middle East respiratory coronavirus (MERS-CoV) receptor-binding domain as an antigen.

PLoS ONE 9(11) , e112602, (2014)

The development of an effective vaccine is critical for prevention of a Middle East respiratory syndrome coronavirus (MERS-CoV) pandemic. Some studies have indicated the receptor-binding domain (RBD) protein of MERS-CoV spike (S) is a good candidate antigen f...

Targeting antigens through blood dendritic cell antigen 2 on plasmacytoid dendritic cells promotes immunologic tolerance.

J. Immunol. 192(12) , 5789-801, (2014)

The C-type lectin receptor blood dendritic cell Ag 2 (BDCA2) is expressed exclusively on human plasmacytoid DCs (pDCs) and plays a role in Ag capture, internalization, and presentation to T cells. We used transgenic mice that express human BDCA2 and anti-BDCA...

Hydrotalcite composites for an effective fluoride buccal administration: a new technological approach.

Int. J. Pharm. 454(1) , 259-68, (2013)

The aim of this work was to develop new mucoadhesive buccal patches containing an inorganic fluorinated compound, MgAl-F, intended for decay prevention. Firstly MgAl-F was synthesized and characterized, then the patches were prepared starting from a physical ...

Fish oil supplementation decreases oxidative stress but does not affect platelet-activating factor bioactivity in lungs of asthmatic rats.

Lipids 49(7) , 665-75, (2014)

Dietary fish oil supplementation increases the content of n-3 polyunsaturated fatty acids (PUFA) in cellular membranes. The highly unsaturated nature of n-3 PUFA could result in an enhanced lipid peroxidation in the oxidative environment characteristic of ast...

Pre-oxidation with KMnO4 changes extra-cellular organic matter's secretion characteristics to improve algal removal by coagulation with a low dosage of polyaluminium chloride.

J. Environ. Sci. (China) 25(3) , 452-9, (2013)

Microcystis aeruginosa was used to study the effect of KMnO4 pre-oxidation on algal removal through coagulation with polyaluminium chloride (PAC). KMnO4 pre-oxidation improved the coagulation efficiency of algal at a low dosage of PAC. The optimal KMnO4 feedi...

Conjugate-like immunogens produced as protein capsular matrix vaccines.

Proc. Natl. Acad. Sci. U. S. A. 112(10) , E1143-51, (2015)

Capsular polysaccharides are the primary antigenic components involved in protective immunity against encapsulated bacterial pathogens. Although immunization of adolescents and adults with polysaccharide antigens has reduced pathogen disease burden, pure poly...

Immunizations with hepatitis B viral antigens and a TLR7/8 agonist adjuvant induce antigen-specific immune responses in HBV-transgenic mice.

Int. J. Infect. Dis. 29 , 31-6, (2014)

The capacity of toll-like receptor (TLR) 7/8 agonist-conjugated hepatitis B virus (HBV) proteins (HBV-Ag) to overcome established hepatitis B surface antigen (HBsAg)-specific immune tolerance was explored.A TLR7/8 agonist, CL097, was conjugated with alum-abso...

PEGylated D-serine dehydratase as a D-serine reducing agent.

J. Pharm. Biomed. Anal. 116 , 34-9, (2015)

D-Serine is an endogenous coagonist for N-methyl-D-aspartate (NMDA) receptors and is involved in excitatory neurotransmission. Excessive receptor activation causes excitotoxicity, leading to various acute and chronic neurological disorders. Decrease in D-seri...

Generation and preclinical immunogenicity study of dengue type 2 virus-like particles derived from stably transfected mosquito cells.

Vaccine 33 , 5613-22, (2015)

Recent phase IIb/III trials of a tetravalent live attenuated vaccine candidate revealed a need for improvement in the stimulation of protective immunity against diseases caused by dengue type 2 virus (DENV-2). Our attempts to develop particulate antigens for ...

The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination.

Proc. Natl. Acad. Sci. U. S. A. 110(52) , 21095-100, (2013)

Vaccines are the most effective agents to control infections. In addition to the pathogen antigens, vaccines contain adjuvants that are used to enhance protective immune responses. However, the molecular mechanism of action of most adjuvants is ill-known, and...