Saccharin
Saccharin structure
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Common Name | Saccharin | ||
|---|---|---|---|---|
| CAS Number | 81-07-2 | Molecular Weight | 183.184 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 438.9±28.0 °C at 760 mmHg | |
| Molecular Formula | C7H5NO3S | Melting Point | 226-229 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 219.3±24.0 °C | |
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Nanocasting of carbon films with interdigitated bimodal three-dimensionally ordered mesopores by template-replica coassembly.
Langmuir 30(41) , 12411-20, (2014) Carbon films with interdigitated bimodal three-dimensionally ordered mesoporosity (ib3DOm) are realized by a scalable nanoreplication process that removes the common need plaguing hard-templating strategies for multistep prefabrication of porous sacrificial t... |
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Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata.
Bioorg. Med. Chem. Lett. 21 , 710-4, (2011) The catalytic activity and the inhibition of a new coral carbonic anhydrase (CA, EC 4.2.1.1), from the scleractinian coral Stylophora pistillata, STPCA-2, has been investigated. STPCA-2 has high catalytic activity for the physiological reaction being less sen... |
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Purification and inhibition studies with anions and sulfonamides of an α-carbonic anhydrase from the Antarctic seal Leptonychotes weddellii.
Bioorg. Med. Chem. 19 , 1847-51, (2011) A high activity α-carbonic anhydrase (CA, EC 4.2.1.1) has been purified from various tissues of the Antarctic seal Leptonychotes weddellii. The new enzyme, denominated lwCA, has a catalytic activity for the physiologic CO(2) hydration to bicarbonate reaction,... |
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Evaluation of ice-tea quality by DART-TOF/MS.
J. Mass Spectrom. 50 , 1214-21, (2015) DART (Direct Analysis in Real Time) coupled with Time-of-Flight Mass Spectrometry (TOF/MS) has been used for analyses of ice-teas. The article focuses on quality and authenticity of ice-teas as one of the most important tea-based products on the market. Twent... |
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Coformer screening using thermal analysis based on binary phase diagrams.
Pharm. Res. 31(8) , 1946-57, (2014) The advent of cocrystals has demonstrated a growing need for efficient and comprehensive coformer screening in search of better development forms, including salt forms. Here, we investigated a coformer screening system for salts and cocrystals based on binary... |
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Artificial sweeteners stimulate adipogenesis and suppress lipolysis independently of sweet taste receptors.
J. Biol. Chem. 288(45) , 32475-89, (2013) G protein-coupled receptors mediate responses to a myriad of ligands, some of which regulate adipocyte differentiation and metabolism. The sweet taste receptors T1R2 and T1R3 are G protein-coupled receptors that function as carbohydrate sensors in taste buds,... |
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Determination of eight artificial sweeteners and common Stevia rebaudiana glycosides in non-alcoholic and alcoholic beverages by reversed-phase liquid chromatography coupled with tandem mass spectrometry.
Anal. Bioanal. Chem 407(5) , 1505-12, (2015) The method for the determination of acesulfame-K, saccharine, cyclamate, aspartame, sucralose, alitame, neohesperidin dihydrochalcone, neotame and five common steviol glycosides (rebaudioside A, rebaudioside C, steviol, steviolbioside and stevioside) in soft ... |
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Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Eur. J. Med. Chem. 45 , 930-40, (2010) A neural model based on a numerical molecular representation using CODES program to predict oral absorption of any structure is described. This model predicts both high and low-absorbed compounds with a global accuracy level of 74%. CODES/ANN methodology show... |
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Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana.
Bioorg. Med. Chem. 20 , 1403-10, (2012) The α-carbonic anhydrase (CA, EC 4.2.1.1) Astrosclerin-3 previously isolated from the living fossil sponge Astrosclera willeyana (Jackson et al., Science 2007, 316, 1893), was cloned, kinetically characterized and investigated for its inhibition properties wi... |
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Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Eur. J. Med. Chem. 46 , 218-28, (2011) In order to minimize the high attrition rate that usually characterizes drug research and development projects, current medicinal chemists aim to characterize both pharmacological and ADME profiles at the beginning of drug R&D initiatives. Thus, the developme... |