N-(8-AMINO-3,6-DIOXAOCTYL)RHODAMINE 6G-AMIDE BIS(TRIFLUOROACETATE)

N-(8-AMINO-3,6-DIOXAOCTYL)RHODAMINE 6G-AMIDE BIS(TRIFLUOROACETATE) Structure
N-(8-AMINO-3,6-DIOXAOCTYL)RHODAMINE 6G-AMIDE BIS(TRIFLUOROACETATE) structure
Common Name N-(8-AMINO-3,6-DIOXAOCTYL)RHODAMINE 6G-AMIDE BIS(TRIFLUOROACETATE)
CAS Number 591742-76-6 Molecular Weight 772.731
Density N/A Boiling Point N/A
Molecular Formula C36H42F6N4O8 Melting Point N/A
MSDS USA Flash Point N/A

A rational approach to tuning the pKa values of rhodamines for living cell fluorescence imaging.

Org. Biomol. Chem. 9 , 1723-1726, (2011)

A novel strategy to systematically tune the pK(a) values of rhodamines is described. This strategy was applied to rationally develop compound 1e with a pK(a) of 6.5, the highest among rhodamine amide derivatives, and it could be employed to detect acidic pH v...