S(-)-Cyanopindolol hemifumarate

S(-)-Cyanopindolol hemifumarate Structure
S(-)-Cyanopindolol hemifumarate structure
Common Name S(-)-Cyanopindolol hemifumarate
CAS Number 874882-72-1 Molecular Weight 690.786
Density N/A Boiling Point N/A
Molecular Formula C36H46N6O8 Melting Point N/A
MSDS USA Flash Point N/A

Characterization of a 5-HT1B receptor on CHO cells: functional responses in the absence of radioligand binding.

Br. J. Pharmacol. 117 , 1119-1126, (1996)

1. Chinese hamster ovary (CHO) cells have been reported to be devoid of 5-HT receptors and have frequently been used as hosts for the expression of cloned 5-HT receptors. Unexpectedly, 5-HT was found to induce profound inhibition of forskolin-stimulated cycli...

Characteristics of cyanopindolol analogues active at the beta 3-adrenoceptor in rat ileum.

Br. J. Pharmacol. 119 , 564-568, (1996)

1. Cyanopindolol (CYP) is a potent antagonist at the beta 3-adrenoceptor in rat ileum. Several analogues of CYP and pindolol were synthesized that also produced antagonist effects at the beta 3-adrenoceptor. However, at high concentrations, these compounds ap...

Differential functional activity of 5-hydroxytryptamine receptor ligands and beta adrenergic receptor antagonists at 5-hydroxytryptamine1B receptor sites in Chinese hamster lung fibroblasts and opossum renal epithelial cells.

J. Pharmacol. Exp. Ther. 270 , 938-945, (1994)

Functional activity of 5-hydroxytryptamine (5-HT) receptor ligands and beta adrenergic receptor antagonists was studied at 5-HT1B receptor sites in Chinese hamster lung (CHL) fibroblasts by measuring two cellular responses: inhibition of forskolin-stimulated ...