4,4'-Dithiobis[2-aminobutyric Acid]
![4,4'-Dithiobis[2-aminobutyric Acid] Structure](https://image.chemsrc.com/caspic/394/870-93-9.png)
4,4'-Dithiobis[2-aminobutyric Acid] structure
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Common Name | 4,4'-Dithiobis[2-aminobutyric Acid] | ||
|---|---|---|---|---|
| CAS Number | 870-93-9 | Molecular Weight | 268.354 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 507.6±50.0 °C at 760 mmHg | |
| Molecular Formula | C8H16N2O4S2 | Melting Point | ≥300 °C | |
| MSDS | Chinese USA | Flash Point | 260.8±30.1 °C | |
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Determination of homocysteine in cerebrospinal fluid as an indicator for surgery treatment in patients with hydrocefalus.
Physiol. Res. 63(4) , 521-7, (2014) Increased homocysteine levels in serum are typical features of neurodegenerative brain diseases including hydrocephalus. The most frequent therapeutic approach consists of the insertion of a shunt, connecting the brain ventricles to an alternative drainage si... |
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Simultaneous determination of cystathionine, total homocysteine, and methionine in dried blood spots by liquid chromatography/tandem mass spectrometry and its utility for the management of patients with homocystinuria.
Clin. Chim. Acta 437 , 211-7, (2014) Disorders of homocysteine and B-vitamin metabolism represent a significant problem in clinical practice. Establishing the diagnosis requires specialized tests with demanding preanalytical requirements. To advance the detection of patients with these disorders... |
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Excess levels of cysteine and homocysteine induce tibial dyschondroplasia in broiler chicks.
J. Nutr. 122 , 482-487, (1992) The effect of excessive levels of cysteine and homocysteine on tibial dyschondroplasia (TD) in broiler chicks was studied. In the first experiment, graded levels of L-cysteine as well as one level of L-homocysteine were supplemented to a corn-soybean-based di... |
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Speciation and determination of thiols in biological samples using high performance liquid chromatography–inductively coupled plasma-mass spectrometry and high performance liquid chromatography–Orbitrap MS
Anal. Chim. Acta 680 , 41-7, (2010) An analytical method was developed for the determination of thiols in biological samples. Reverse phase chromatography coupled to ICP quaduropole MS or Orbitrap MS was employed for the separation and detection of thiols. For the determination of total thiols,... |
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Derivatization of GSSG by pHMB in alkaline media. Determination of oxidized glutathione in blood.
Talanta 82 , 815-20, (2010) Chromatographic determination of glutathione disulfide (GSSG) without any preliminary reduction has been presented using GSSG derivatization by p-hydroxymercuribenzoate (pHMB) in strong alkaline medium followed by the determination of GS-pHMB complex by rever... |
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Saratin (an inhibitor of platelet-collagen interaction) decreases platelet aggregation and homocysteine-mediated postcarotid endarterectomy intimal hyperplasia in a dose-dependent manner.
Am. J. Surg. 188 , 778-785, (2004) This study investigated Saratin's (Merck KGaA, Darmstadt, Germany) prevention of platelet adhesion and intimal hyperplasia at different doses and in the hyperhomocystinemia rat carotid endarterectomy (CEA) model.Rats were divided into two groups: (1) platelet... |
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Use of bioimpedance spectroscopy to estimate body water distribution in rats fed high dietary sulfur amino acids.
J. Nutr. 131 , 1302-1308, (2001) The effect of dietary sulfur amino acids on bioelectric properties was studied in rats by using bioimpedance spectroscopy. Weanling rats were assigned to one of 12 groups in a factorially arranged experiment with dietary variables of supplemental sulfur amino... |
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Gas-Phase Unimolecular Dissociation Reveals Dominant Base Property of Protonated Homocysteine Sulfinyl Radical Ions.
Chemistry 22 , 934-40, (2016) Homocysteine sulfinyl radical ((SO⋅) Hcy) is a reactive intermediate involved during oxidative damage of DNA in the presence of high concentrations of homocysteine (Hcy). The short lifetime of (SO⋅) Hcy makes its preparation, isolation, and characterization c... |
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Development of a reliable method based on ultra-performance liquid chromatography coupled to tandem mass spectrometry to measure thiol-associated oxidative stress in whole blood samples.
J. Pharm. Biomed. Anal. 123 , 104-12, (2016) The aminothiols are biological compounds with numerous vital functions. One of the most relevant is their role as antioxidant systems. The reduced to oxidized ratios are extremely useful indicators of oxidative stress and cellular redox status. We have valida... |