HEPARIN MONOSULFATE SODIUM SALT

HEPARIN MONOSULFATE SODIUM SALT Structure
HEPARIN MONOSULFATE SODIUM SALT structure
Common Name HEPARIN MONOSULFATE SODIUM SALT
CAS Number 57459-72-0 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS USA Flash Point N/A

Synergistic Binding of Vascular Endothelial Growth Factor-A and Its Receptors to Heparin Selectively Modulates Complex Affinity.

J. Biol. Chem. 290 , 16451-62, (2015)

Angiogenesis is a highly regulated process orchestrated by the VEGF system. Heparin/heparan sulfate proteoglycans and neuropilin-1 (NRP-1) have been identified as co-receptors, yet the mechanisms of action have not been fully defined. In the present study, we...

Glycosaminoglycan sulfation determines the biochemical properties of prion protein aggregates.

Glycobiology 25 , 745-55, (2015)

Prion diseases are transmissible neurodegenerative disorders associated with the conversion of the cellular prion protein, PrP(C), to a misfolded isoform called PrP(Sc). Although PrP(Sc) is a necessary component of the infectious prion, additional factors, or...

Delivering heparin-binding insulin-like growth factor 1 with self-assembling peptide hydrogels.

Tissue Eng. Part A 21(3-4) , 637-46, (2015)

Heparin-binding insulin-like growth factor 1 (HB-IGF-1) is a fusion protein of IGF-1 with the HB domain of heparin-binding epidermal growth factor-like growth factor. A single dose of HB-IGF-1 has been shown to bind specifically to cartilage and to promote su...

Heparan sulfate proteoglycan on leukemic cells is primarily involved in integrin triggering and its mediated adhesion to endothelial cells.

J. Exp. Med. 184 , 1987-1997, (1996)

Leukocyte migration from circulation into tissue depends on leukocyte integrin-mediated adhesion to endothelium, but integrins cannot function until activated. However, it remains to be understood how tumor cells adhere to endothelium and infiltrate into unde...

Regional distribution of neural cell adhesion molecule immunoreactivity in the adult rat telencephalon and diencephalon. Partial colocalization with heparan sulfate proteoglycan immunoreactivity.

Brain Res. 746 , 25-33, (1997)

In the present paper immunocytochemical analysis at the fluorescence microscopical level has been performed of neural cell adhesion. molecule (NCAM) immunoreactivity in the adult rat tel- and diencephalon in order to further substantiate the highly selective ...

The Synthetic Antimicrobial Peptide 19-2.5 Interacts with Heparanase and Heparan Sulfate in Murine and Human Sepsis.

PLoS ONE 10 , e0143583, (2015)

Heparanase is an endo-β-glucuronidase that cleaves heparan sulfate side chains from their proteoglycans. Thereby, heparanase liberates highly potent circulating heparan sulfate-fragments (HS-fragments) and triggers the fatal and excessive inflammatory respons...

The heparan sulfate suleparoide inhibits rat corneal angiogenesis and in vitro neovascularization.

Exp. Eye Res. 67(2) , 133-42, (1998)

The purpose of this study was to evaluate the inhibitory activity of the heparan sulfate suleparoide on vascular cell growth in vitro and angiogenesis in vivo. Human HUV-EC-C endothelial cell proliferation and microvessel sprouting from cultured rat aortic ri...

Comparative pharmacologic profile of a glycosaminoglycan mixture, Sulodexide, and a chemically modified heparin derivative, Suleparoide.

Semin. Thromb. Hemost. 19 Suppl 1 , 49-57, (1993)

Effect of suleparoide on fibrinolysis in the anterior chamber of rabbits.

Ophthalmic Res. 28(3) , 176-83, (1996)

Intra-ocular fibrin deposition following ocular surgery is a serious postoperative complication. The current management of severe postoperative fibrin response is usually ineffective. A quantitative model of fibrin deposition in the rabbit anterior chamber wa...

Structure and function of heparan sulphate proteoglycans.

Biochem. J. 236 , 313, (1986)