Glutamate oxidase
Glutamate oxidase structure
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Common Name | Glutamate oxidase | ||
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| CAS Number | 39346-34-4 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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A stable and selective electrochemical biosensor for the liver enzyme alanine aminotransferase (ALT).
Biosens. Bioelectron. 24(9) , 2926-30, (2009) An electrochemical method to determine alanine aminotransferase (ALT) activity over its normal and elevated physiological range was developed based upon detection of L-glutamate at a glutamate oxidase-modified platinum electrode. Measurements were carried out... |
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Simultaneous determination of L- and D-methotrexate using a sequential injection analysis/amperometric biosensors system.
Biosens. Bioelectron. 19(3) , 261-7, (2003) A sequential injection analysis (SIA) is proposed for the simultaneous determination of L- and D-methotrexate (Mtx) using amperometric biosensors as detectors. A SIA system is proposed due to the highest precision and accuracy and lower consumption of sample ... |
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Pt/Au bimetallic hierarchical structure with micro/nano-array via photolithography and electrochemical synthesis: From design to GOT and GPT biosensors.
Talanta 78(4-5) , 1371-7, (2009) A novel matrix for enzyme immobilization was successfully developed by using Pt/Au bimetallic hierarchical structure with micro/nano-array to generate highly sensitive biosensors for glutamic oxaloacetic transaminase (GOT, EC 2.6.1.1) and glutamic pyruvic tra... |
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Imaging of L-glutamate fluxes in mouse brain slices based on an enzyme-based membrane combined with a difference-image analysis.
Anal. Chem. 75(15) , 3775-83, (2003) A time-resolved imaging method for visualizing L-glutamate release in mammalian brain slices is proposed by using an enzyme membrane combined with a difference-image analysis. The enzyme membrane is composed of L-glutamate oxidase and horseradish peroxidase i... |
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Real-time monitoring of L-glutamate release from mouse brain slices under ischemia with a glass capillary-based enzyme electrode.
Anal. Bioanal. Chem 383(4) , 660-7, (2005) Real-time monitoring of L-glutamate release from various neuronal regions of mouse hippocampal slices under ischemia (a glucose-free hypoxia condition) is described. A glass capillary microelectrode with a tip size of approximately 10 microm containing a very... |
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Structural characterization of L-glutamate oxidase from Streptomyces sp. X-119-6.
FEBS J. 276(14) , 3894-903, (2009) L-Glutamate oxidase (LGOX) from Streptomyces sp. X-119-6, which catalyzes the oxidative deamination of L-glutamate, has attracted increasing attention as a component of amperometric L-glutamate sensors used in the food industry and clinical biochemistry. The ... |
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Interaction of L-glutamate oxidase with triazine dyes: selection of ligands for affinity chromatography.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 807(2) , 277-85, (2004) Glutamate oxidase (GOX, EC 1.4.3.11) from Streptomyces catalyses the oxidation of L-glutamate to alpha-ketoglutarate. Its kinetic constants for L-glutamate were measured equal to 2 mM for Km and 85.8 s(-1) for kcat. BLAST search and amino acid sequence alignm... |
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Receptors and enzymes for medical sensing of L-glutamate.
Mini Rev. Med. Chem. 6(10) , 1091-100, (2006) Medical sensing systems using isolated or intact glutamate receptor (GluR) ion channels and glutamate oxidase (GluOx) are discussed for L-glutamate, one of the principal neurotransmitter in the central nervous systems of mammalian brain, and related agonists.... |
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Arg305 of Streptomyces L-glutamate oxidase plays a crucial role for substrate recognition.
Biochem. Biophys. Res. Commun. 417(3) , 951-5, (2012) Recently, we have solved the crystal structure of L-glutamate oxidase (LGOX) from Streptomyces sp. X-119-6 (PDB code: 2E1M), the substrate specificity of which is strict toward L-glutamate. By a docking simulation using L-glutamate and structure of LGOX, we s... |
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Enzyme-immobilized CNT network probe for in vivo neurotransmitter detection.
Methods Mol. Biol. 743 , 65-75, (2011) Glutamate is the principal excitatory neurotransmitter in the brain, and its excessive release plays a key role in neuronal death associated with a wide range of neural disorders. Real-time monitoring of extracellular glutamate levels would be very helpful in... |