PEFACHROME(R) UPA*

PEFACHROME(R) UPA* Structure
PEFACHROME(R) UPA* structure
Common Name PEFACHROME(R) UPA*
CAS Number 112283-16-6 Molecular Weight 586.603
Density N/A Boiling Point N/A
Molecular Formula C24H30N8O6.C2H4O2 Melting Point N/A
MSDS USA Flash Point N/A

A new chromogenic test for the detection of urokinase in the genus Shigella.

Microbiologica (Bologna) 10 , 331, (1987)

A simple test for detection of urokinase in Shigella is described. The test is performed by suspending a loopful of bacteria in 100 microliters of a buffered 1mM solution of benzoyl-beta-alanyl glycyl-arginyl-4-nitroanilide acetate (Chromozym U). Enzymatic ac...

Urokinase-type plasminogen activator (uPA) and matrix metalloproteinase-9 (MMP-9) expression and activity during early embryo development in the cow. Whiteside EJ, Kan M, Jackson MM, et al.

Anat. Embryol. 204 , 477-483, (2001)

No activation of urokinase plasminogen activator by anti-desmoglein 3 monoclonal IgG antibodies in cultured human keratinocytes.

J. Dermatol. Sci. 47 , 119-125, (2007)

Although pemphigus vulgaris (PV)-IgG has been shown to activate urokinase plasminogen activator (uPA) in cultured keratinocytes, activation of uPA is thought to have no primary role in PV-acantholysis, because PV-IgG is still pathogenic in uPA- and tissue-PA-...

Urokinase activity after freezing: implications for thrombolysis in intraventricular hemorrhage.

Am. J. Health Syst. Pharm. 56 , 2047-2051, (1999)

The retention of urokinase activity after frozen storage was studied. Urokinase powder was reconstituted aseptically in sterile water for injection or preservative-free 0.9% sodium chloride injection to a final concentration of 5000 IU/mL. Samples were stored...

Substrate-induced changes in protease active site conformation impact on subsequent reactions with substrates.

J. Biol. Chem. 285(30) , 22950-6, (2010)

Enzymatic catalysis of biochemical reactions is essential to all living systems. The "lock and key" and "induced fit" models were early contributions to our understanding of the mechanisms involved in the reaction between an enzyme and its substrate. However,...